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等待全膝关节置换术的中国绝经后妇女骨质疏松患病率和危险因素
Authors Tao Y, Tang S, Huang X, Wang H, Zhou A, Zhang J
Received 17 December 2020
Accepted for publication 10 February 2021
Published 26 February 2021 Volume 2021:16 Pages 379—387
DOI https://doi.org/10.2147/CIA.S297947
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 4
Editor who approved publication: Prof. Dr. Zhi-Ying Wu
Background: Total knee arthroplasty (TKA) complications associated with low bone quality are challenging for orthopaedic surgeons to treat, but little is known about bone quality in Chinese postmenopausal women awaiting TKA. This study investigated the incidence of osteoporosis (OP) and explored the preoperative risk factors for OP in this population.
Methods: We retrospectively reviewed the data of Chinese postmenopausal women who were indicated for TKA between May 2017 and June 2020. The bone mineral density (BMD) of the hip and lumbar spine and multiple preoperative parameters were collected and analyzed. Binary logistic regression analysis was performed to identify independent risk factors for OP in this population.
Results: A total of 204 postmenopausal women with advanced knee OA were included in the study (age: 69.7± 8.5 years; body mass index [BMI]: 25.5± 4.0 kg/m2). The OP prevalence among all participants was 59.8%, and the patients aged 60– 80 years had a significantly lower BMD than did the age/ethnicity-adjusted population. An age ≥ 60 years, a BMI< 25, and the presence of a varus knee deformity were independent risk factors for preoperative OP in the postmenopausal women awaiting TKA.
Conclusion: The prevalence of OP in Chinese postmenopausal women awaiting TKA is higher than that in the age/ethnicity-adjusted normal population. An age ≥ 60 years, a BMI< 25, and the presence of a varus knee deformity are independent risk factors that can be used to predict preoperative OP in this population.
Keywords: osteoporosis, postmenopausal women, total knee arthroplasty, Chinese, bone mineral density