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用于伤口愈合应用的多糖电纺纳米纤维
Authors Tan G, Wang L, Pan W , Chen K
Received 6 May 2022
Accepted for publication 23 July 2022
Published 6 September 2022 Volume 2022:17 Pages 3913—3931
DOI https://doi.org/10.2147/IJN.S371900
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Yan Shen
Abstract: As a type of biological macromolecule, natural polysaccharides have been widely used in wound healing due to their low toxicity, good biocompatibility, degradability and reproducibility. Electrospinning is a versatile and simple technique for producing continuous nanoscale fibers from a variety of natural and synthetic polymers. The application of electrospun nanofibers as wound dressings has made great progress and they are considered one of the most effective wound dressings. This paper reviews the preparation of polysaccharide nanofibers by electrospinning and their application prospects in the field of wound healing. A variety of polysaccharide nanofibers, including chitosan, starch, alginate, and hyaluronic acid are introduced. The preparation strategy of polysaccharide electrospun nanofibers and their functions in promoting wound healing are summarized. In addition, the future prospects and challenges for the preparation of polysaccharide nanofibers by electrospinning are also discussed.
Keywords: polysaccharide, electrospun nanofibers, wound healing, preparation strategy, function