论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
Authors Zhu L, Ni Z, Luo X, Zhang Z, Wang S, Meng Z, Gu X, Wang X
Received 15 November 2017
Accepted for publication 15 December 2017
Published 21 February 2018 Volume 2018:13 Pages 645—652
DOI https://doi.org/10.2147/COPD.S157084
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Charles Downs
Peer reviewer comments 2
Editor who approved publication: Prof. Dr. Chunxue Bai
Purpose: Chronic
bronchitis is thought to occur in elderly patients, and smoking seems to be an
important risk factor. The outcomes related to the age of onset in patients
with chronic bronchitis are still unclear.
Patients and
methods: A retrospective study was conducted
on deceased patients whose diagnosis included bronchitis from 2010 to 2016.
Patients were separated into two groups according to the age of onset (Group I,
age ≤50 years old; Group II, age >50 years old). Information regarding
disease course, smoking history, death age, number of admissions per year, Hugh
Jones Index, and self-reported comorbidities of the patients was recorded.
Results: The courses of chronic cough and sputum were 33.38±7.73 years and
14.44±8.60 years in Group I and Group II, respectively (p <0.05). The death ages of
Group I and Group II were 77.65±7.87 years and 84.69±6.67 years,
respectively (p <0.05). There was a
significant negative correlation between the number of hospital admissions per
year and the age of onset. The age of onset was negatively associated with
daily smoking count (r =-0.210) and total
smoking count (r =-0.146). In Group I, there were
fewer cases of coronary heart disease (OR =0.41 [0.24–0.71]), neurological
diseases (OR =0.48 [0.24–0.97]), and total comorbidities (OR =0.67
[0.54–0.85]) than in Group II.
Conclusion: Patients with early onset chronic bronchitis had a longer history,
younger death age, poorer health status, and lower incidence of comorbidities.
Keywords: chronic airway disease, comorbidity, Hugh Jones Index, smoking,
hospital admission, disease course