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已发表论文
利用抗抑郁药提高精神分裂症治疗的效果： 好处与风险
Authors Mao YM, Zhang MD
Published Date March 2015 Volume 2015:11 Pages 701—713
DOI http://dx.doi.org/10.2147/NDT.S62266
Received 11 February 2014, Accepted 20 October 2014, Published 16 March 2015
Abstract: We focused on the application of antidepressants in schizophrenia
treatment in this review. Augmentation of antidepressants with antipsychotics
is a common clinical practice to treat resistant symptoms in schizophrenia,
including depressive symptoms, negative symptoms, comorbid obsessive–compulsive
symptoms, and other psychotic manifestations. However, recent systematic review
of the clinical effects of antidepressants is lacking. In this review, we have
selected and summarized current literature on the use of antidepressants in
patients with schizophrenia; the patterns of use and effectiveness, as well as
risks and drug–drug interactions of this clinical practice are discussed in
detail, with particular emphasis on the treatment of depressive symptoms in schizophrenia.
Keywords: depressive symptoms, drug-drug interaction, antipsychotics
Keywords: depressive symptoms, drug-drug interaction, antipsychotics
