已发表论文

外泌体作为癌症治疗的主动靶向的纳米载体

 

Authors Wang Y, Zhang Y, Cai G, Li Q

Received 21 November 2019

Accepted for publication 25 May 2020

Published 17 June 2020 Volume 2020:15 Pages 4257—4273

DOI https://doi.org/10.2147/IJN.S239548

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Mian Wang

Abstract: In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes.
Keywords: exosomes, nanocarriers, function, tumor therapy




Figure 2 Usually, exosomes can be naturally secreted by a variety of cells, such as...