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外泌体作为癌症治疗的主动靶向的纳米载体
Authors Wang Y, Zhang Y, Cai G, Li Q
Received 21 November 2019
Accepted for publication 25 May 2020
Published 17 June 2020 Volume 2020:15 Pages 4257—4273
DOI https://doi.org/10.2147/IJN.S239548
Checked for plagiarism Yes
Review by Single-blind
Peer reviewer comments 3
Editor who approved publication: Dr Mian Wang
Abstract: In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes.
Keywords: exosomes, nanocarriers, function, tumor therapy
