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人脐带间充质干细胞用于 COVID-19 危重患者的辅助治疗:1 份病例报告
Authors Zhu Y, Zhu R, Liu K, Li X, Chen D, Bai D, Luo J, Liu Y, Zhang Y, Li L, Hu J, Xu D, Liu Y, Zhao RC
Received 17 July 2020
Accepted for publication 3 September 2020
Published 28 September 2020 Volume 2020:13 Pages 3295—3300
DOI https://doi.org/10.2147/IDR.S272645
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Suresh Antony
Background: COVID-19 (coronavirus disease 2019) has become a global public health emergency since patients were first detected in Wuhan, China, in December 2019. Currently, there are no satisfying antiviral medications and vaccines available.
Case Presentation: We reported the treatment process and clinical outcome of a 48-year-old man critically ill COVID-19 patient who received transfusion of allogenic human umbilical cord mesenchymal stem cells (UC-MSCs).
Conclusions: We proposed that UC-MSC transfusion might be a new option for critically ill COVID-19. Although only one case we were shown, more similar clinical cases are inquired for further evidence providing the potential effectiveness of UC-MSC treatment.
Keywords: COVID-19, UC-MSCs, critically ill, cell transplantation, case report
