已发表论文

肺多形性癌对 Camrelizumab(PD1 单克隆抗体)单一疗法的部分反应:一病例报告

 

Authors Chen Y, Zhang H, Shi J, Wang T

Received 27 August 2020

Accepted for publication 27 October 2020

Published 3 December 2020 Volume 2020:13 Pages 12471—12476

DOI https://doi.org/10.2147/OTT.S279004

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Federico Perche


Abstract: We report a case of a 68-year-old man diagnosed with pulmonary pleomorphic carcinoma who showed partial response after a single treatment with camrelizumab (PD1 monoclonal antibody). The patient’s tumor was positive for programmed cell death ligand 1 (PD-L1) and progressed rapidly after a course of chemotherapy. Fortunately, the tumors dramatically shrank after one cycle of camrelizumab, an anti-programmed cell death-1 (PD-1) antibody developed by Chinese Hengrui Medicine. In conclusion, camrelizumab may be a good treatment option, especially in tumors that express PD-L1.
Keywords: camrelizumab, pulmonary pleomorphic carcinoma, immune checkpoint inhibitor, PD-1, reactive skin capillary endothelial cell proliferation, RCCEP