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面对胃癌中的细胞自噬我们目前了解什么?
Authors Xiu T, Guo Q, Jing FB
Received 23 December 2020
Accepted for publication 12 March 2021
Published 3 May 2021 Volume 2021:14 Pages 1647—1659
DOI https://doi.org/10.2147/IJGM.S298705
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Scott Fraser
摘要:自噬是肿瘤细胞溶酶体中错误折叠的蛋白质和受损的细胞器被降解、再利用分解的物质、避免大量有害物质积累的过程。本文就自噬在胃癌恶性转化中的作用、自噬标志物、胃癌细胞自噬调节机制以及靶向自噬在胃癌治疗中的应用进行总结讨论。
Keywords: autophagy, gastric cancer, autophagy-related genes, lysosomes, targeted therapy