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壬二酸的作用机制与临床应用
Authors Feng X , Shang J, Gu Z, Gong J, Chen Y, Liu Y
Received 2 July 2024
Accepted for publication 27 September 2024
Published 22 October 2024 Volume 2024:17 Pages 2359—2371
DOI https://doi.org/10.2147/CCID.S485237
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Jeffrey Weinberg
摘要：壬二酸（AZA）是一种含有九个碳原子的非酚类饱和二羧酸，由马拉色菌自然产生。它具有多种生理活性，包括抗菌、抗角化、抑制黑色素生成、抗氧化和抗炎作用。AZA在皮肤科广泛应用，并获得美国食品药品监督管理局（FDA）批准用于治疗丘疹脓疱型酒渣鼻。同时，它在治疗寻常痤疮和黄褐斑方面也显示出显著疗效。本文综述了AZA的作用机制及其临床应用，旨在为其临床和化妆品应用提供理论支持，并促进进一步的研究。