109451
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.4 Breast Cancer (Dove Med Press)
- 3.2 Clin Epidemiol
- 2.6 Cancer Manag Res
- 2.9 Infect Drug Resist
- 3.7 Clin Interv Aging
- 5.1 Drug Des Dev Ther
- 3.1 Int J Chronic Obstr
- 6.6 Int J Nanomed
- 2.6 Int J Women's Health
- 2.9 Neuropsych Dis Treat
- 2.8 OncoTargets Ther
- 2.0 Patient Prefer Adher
- 2.2 Ther Clin Risk Manag
- 2.5 J Pain Res
- 3.0 Diabet Metab Synd Ob
- 3.2 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 1.8 Pharmgenomics Pers Med
- 2.0 Risk Manag Healthc Policy
- 4.1 J Inflamm Res
- 2.0 Int J Gen Med
- 3.4 J Hepatocell Carcinoma
- 3.0 J Asthma Allergy
- 2.2 Clin Cosmet Investig Dermatol
- 2.4 J Multidiscip Healthc
体外膜肺氧合救治免疫检查点抑制剂相关肺炎合并重度ARDS患者1例
Authors Meng Y, Yuan Y, Ma L, Wang J, Zhang B
Received 2 December 2024
Accepted for publication 15 March 2025
Published 26 March 2025 Volume 2025:18 Pages 411—419
DOI https://doi.org/10.2147/IMCRJ.S507273
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Vinay Kumar
摘要：本文回顾性分析1例肺恶性肿瘤术后使用替雷利珠单抗所致免疫相关性肺炎合并重度ARDS患者的诊疗经过：前期有创机械通气实施肺保护性通气策略氧合未改善，遂行静脉-静脉体外膜肺氧合（VV-ECMO），期间发生导管相关感染、溶血、膜肺血栓形成等并发症，后实施清醒VV-ECMO，仍存在撤机困难，再次鉴别疾病明确诊断为免疫检查点抑制剂相关肺炎，规范治疗后最终得以好转。对于已接受有创机械通气的重度ARDS患者，首先应规范实施肺保护性通气策略、条件允许下俯卧位通气，若氧合仍不能改善，结合心功能选择体外膜肺氧合方式，实施ECMO，熟练掌握相关并发症及处理；另斟酌清醒ECMO利弊，学会鉴别发热伴肺部阴影相关疾病以精准治疗。