Hengzhong Lun,1,* Shujing Sui,2,* Zhijun Zhang,1 Meijie Jiang1 

1Department of Laboratory Medicine, The Affiliated Tai’an City Central Hospital of Qingdao University, Tai’an, 271000, People’s Republic of China; 2Department of Gastroenterology, The Affiliated Taian City Central Hospital of Qingdao University, Tai’an, 271000, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Zhijun Zhang, The Affiliated Tai’an City Central Hospital of Qingdao University, Tai’an, Shandong, People’s Republic of China, Email ghwtzzj@qdu.edu.cn Meijie Jiang, The Affiliated Tai’an City Central Hospital of Qingdao University, Tai’an, Shandong, People’s Republic of China, Email xtingw@126.com

Abstract: Eosinophilic gastrointestinal diseases (EGIDs) are chronic, progressive, immune-mediated inflammatory conditions. Its delayed diagnosis and treatment are often due to the lack of specific clinical manifestations. Klebsiella pneumoniae is usually considered normal flora of the gut and rarely causes intestinal infections. In this case report, we present a rare case of intestinal mucosal exfoliation associated with K. pneumoniae infection following eosinophilic enteritis, which was cured by intravenous levofloxacin and oral prednisone acetate and montelukast. This case highlights the importance of considering these conditions in patients presenting with clinical diarrhea when the cause of the disease can not be found and enhancing disease understanding.

Keywords: eosinophilic gastrointestinal, klebsiella pneumoniae, intestinal infection, diarrhea