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联合超声乳化白内障吸除术与角膜缘松解切口术对眼表组织损伤的比较与标准超声乳化白内障吸除术
Authors Wang H , Yu X, Li Y, Sun L, Liu M, Zhang X, Yang R
Received 6 June 2025
Accepted for publication 28 July 2025
Published 13 August 2025 Volume 2025:19 Pages 2743—2750
DOI https://doi.org/10.2147/OPTH.S534006
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Scott Fraser
Haiyan Wang,1,2 Xinlu Yu,3 Yanan Li,2 Lingjuan Sun,2 Mingqi Liu,2 Xiongwei Zhang,4 Ruibo Yang1
1Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, Tianjin, 300384, People’s Republic of China; 2Department of Ophthalmology, Shijiazhuang People’s Hospital, Shijiazhuang, Hebei, 050000, People’s Republic of China; 3Department of Ophthalmology, Maternal and Child Health Hospital of Qinhuangdao City, Qinhuangdao, Hebei, 066000, People’s Republic of China; 4Department of Nuclear Medicine, Shijiazhuang People’s Hospital, Shijiazhuang, Hebei, 050000, People’s Republic of China
Correspondence: Ruibo Yang, Tianjin Key Laboratory of Retinal Functions and Diseases, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, Tianjin, 300384, People’s Republic of China, Email yangruibo771@163.com Xiongwei Zhang, Department of Nuclear Medicine, Shijiazhuang People’s Hospital, Shijiazhuang, Hebei, 050000, People’s Republic of China, Email 89286960@qq.com
Purpose: To investigate the effect of phacoemulsification combined with LRIs on the ocular surface at different postoperative time.
Design: This study was designed as a retrospective analysis. Medical records of patients who had undergone relevant surgeries in the past were reviewed. Patients were divided into two groups based on the surgical procedures they had received: one group was those who had undergone phacoemulsification combined with LRIs (experimental group), and the other was those who had only received phacoemulsification (control group).
Methods: We retrospectively selected 80 patients (80 eyes) who had received cataract treatment. Among them, 41 eyes belonged to the experimental group and 39 eyes to the control group, which were grouped according to the degree of astigmatism as recorded in the medical files. The Tear Film Objective Scatter Index (TF-OSI), tear film break-up time (BUT), Schirmer I test, and Ocular Surface Disease Index (OSDI) scores were utilized to retrospectively evaluate the ocular surface conditions of these patients.
Results: A total of 80 patients (80 eyes) were selected for phacoemulsification treatment with cataract, TF-OSI value of the experimental group was higher than that of the control group at 1 day, 1 week, 6 weeks after surgery (P < 0.05). BUT value was lower than that of the control group at 1 day, 1 week, 6 weeks after surgery (P < 0.05). Schirmer I test value was lower than that of the control group at 1 week and 6 weeks after surgery (P < 0.05). OSDI scores were higher than that of the control group 1 week, 6 weeks and 3 months after surgery (P < 0.05).
Conclusion: Phacoemulsification with LRIs may cause more tissue damage on the ocular surface compared to standard phacoemulsification alone.
Keywords: phacoemulsification, limbal relaxing incisions, corneal astigmatism, ocular surface, tear film objective scatter index