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已发表论文
针对高甘油三酯血症诱发的急性胰腺炎制定健康素养干预措施：一个恰当把握时机的框架
Authors Chen W, Yin P, Yang X, Ma S, Zheng X, Fang F, Su X
Received 15 May 2025
Accepted for publication 3 October 2025
Published 21 October 2025 Volume 2025:19 Pages 3225—3237
DOI https://doi.org/10.2147/PPA.S540742
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Johnny Chen
Weiwei Chen,1,* Ping Yin,2,* Xiaoxi Yang,3 Shuli Ma,4 Xinmei Zheng,1 Fang Fang,5 Xia Su2,6
1Medical College of Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China; 2Hepatobiliary and Pancreatic Center, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China; 3Southern College, Sun Yat-Sen University, Gangzhou, Guangdong, People’s Republic of China; 4Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People’s Republic of China; 5Nursing Department, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China; 6School of Nursing, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Fang Fang, Nursing Department, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China, Email ffzyzxnokl@163.com Xia Su, Hepatobiliary and Pancreatic Center, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China, Email suxia1014@outlook.com
Objective: To develop a health literacy intervention program for patients with hypertriglyceridemia-induced acute pancreatitis based on Timing It Right.
Methods: Guided by the Timing It Right framework, a preliminary version of the intervention program was developed through a comprehensive literature review and semi-structured interviews. From August to October 2023, two rounds of Delphi expert consultations were carried out with a panel of 15 medical and nursing experts from four provinces and municipalities (Jiangsu, Sichuan, Heilongjiang, and Shanghai). The feedback obtained through this process was used to refine and finalize the intervention program.
Results: Following two rounds of consultation, a consensus was reached among all 15 experts. The authority coefficients of the experts were 0.825 and 0.813, respectively, with a 100% response rate. The Kendall’s coefficients of concordance were 0.203 and 0.206 (P < 0.001). In the second round, the coefficients of variation for all items ranged from 0.071 to 0.188. The final health literacy intervention program comprised 4 first-level items, 10 second-level items, and 52 third-level items.
Conclusion: The health literacy intervention program developed using the Timing It Right framework demonstrates scientific validity, reliability, feasibility, and practical applicability. It effectively addresses the clinical needs of patients and offers structured guidance for enhancing their health literacy. Further clinical validation is warranted to confirm its effectiveness.
Keywords: hypertriglyceridemia, acute pancreatitis, timing it right, health literacy, delphi technique, nursing
1Medical College of Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China; 2Hepatobiliary and Pancreatic Center, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China; 3Southern College, Sun Yat-Sen University, Gangzhou, Guangdong, People’s Republic of China; 4Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People’s Republic of China; 5Nursing Department, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China; 6School of Nursing, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Fang Fang, Nursing Department, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China, Email ffzyzxnokl@163.com Xia Su, Hepatobiliary and Pancreatic Center, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China, Email suxia1014@outlook.com
Objective: To develop a health literacy intervention program for patients with hypertriglyceridemia-induced acute pancreatitis based on Timing It Right.
Methods: Guided by the Timing It Right framework, a preliminary version of the intervention program was developed through a comprehensive literature review and semi-structured interviews. From August to October 2023, two rounds of Delphi expert consultations were carried out with a panel of 15 medical and nursing experts from four provinces and municipalities (Jiangsu, Sichuan, Heilongjiang, and Shanghai). The feedback obtained through this process was used to refine and finalize the intervention program.
Results: Following two rounds of consultation, a consensus was reached among all 15 experts. The authority coefficients of the experts were 0.825 and 0.813, respectively, with a 100% response rate. The Kendall’s coefficients of concordance were 0.203 and 0.206 (P < 0.001). In the second round, the coefficients of variation for all items ranged from 0.071 to 0.188. The final health literacy intervention program comprised 4 first-level items, 10 second-level items, and 52 third-level items.
Conclusion: The health literacy intervention program developed using the Timing It Right framework demonstrates scientific validity, reliability, feasibility, and practical applicability. It effectively addresses the clinical needs of patients and offers structured guidance for enhancing their health literacy. Further clinical validation is warranted to confirm its effectiveness.
Keywords: hypertriglyceridemia, acute pancreatitis, timing it right, health literacy, delphi technique, nursing