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已发表论文
带状疱疹合并耐甲氧西林金黄色葡萄球菌感染的临床管理
Authors Chen X , Yu Q, Chang D, Sun L
Received 20 August 2025
Accepted for publication 19 November 2025
Published 27 November 2025 Volume 2025:18 Pages 3173—3177
DOI https://doi.org/10.2147/CCID.S560837
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Jeffrey Weinberg
Xinlong Chen,1 Qiao Yu,1 Degui Chang,2 Lisha Sun3
1Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Andrology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 3Department of Endocrinology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China
Correspondence: Lisha Sun, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China, Email sunlisha2025@163.com Degui Chang, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China, Email 13654876569@163.com
Abstract: A 59-year-old male presented with a 10-day history of erythematous vesicular lesions on the left chest and shoulder, accompanied by pain in the back. Clinical examination revealed grouped vesicles with some ulceration and exudate, leading to a diagnosis of herpes zoster. After a clear diagnosis, antiviral treatment with valacyclovir and pain relief with pregabalin was administered. Apply povidone-iodine and normal saline (in a 1:10 ratio) externally, once a day, for 30 minutes each time. One week later, the lesions developed ulcers and crusts, with increased exudate; cultures yielded a significant growth of Methicillin-resistant Staphylococcus aureus(MRSA). Based on the drug sensitivity results, cefuroxime combined with levofloxacin was administered for anti-infection treatment. Following two weeks of treatment, the patient showed significant clinical improvement. The patient’s rashes have significantly subsided, the ulcers have healed and scabbed over, and the exudation has noticeably decreased. Herpes zoster combined with MRSA infection makes the treatment more complicated. This case illustrates the complexities of managing herpes zoster with MRSA and highlights the importance of comprehensive diagnostic and treatment strategies.
Keywords: herpes zoster, MRSA
1Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Andrology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 3Department of Endocrinology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China
Correspondence: Lisha Sun, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China, Email sunlisha2025@163.com Degui Chang, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China, Email 13654876569@163.com
Abstract: A 59-year-old male presented with a 10-day history of erythematous vesicular lesions on the left chest and shoulder, accompanied by pain in the back. Clinical examination revealed grouped vesicles with some ulceration and exudate, leading to a diagnosis of herpes zoster. After a clear diagnosis, antiviral treatment with valacyclovir and pain relief with pregabalin was administered. Apply povidone-iodine and normal saline (in a 1:10 ratio) externally, once a day, for 30 minutes each time. One week later, the lesions developed ulcers and crusts, with increased exudate; cultures yielded a significant growth of Methicillin-resistant Staphylococcus aureus(MRSA). Based on the drug sensitivity results, cefuroxime combined with levofloxacin was administered for anti-infection treatment. Following two weeks of treatment, the patient showed significant clinical improvement. The patient’s rashes have significantly subsided, the ulcers have healed and scabbed over, and the exudation has noticeably decreased. Herpes zoster combined with MRSA infection makes the treatment more complicated. This case illustrates the complexities of managing herpes zoster with MRSA and highlights the importance of comprehensive diagnostic and treatment strategies.
Keywords: herpes zoster, MRSA