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已发表论文
晚期艾滋病患者并发致命猴痘：一例报告
Authors Lu Y , Yu X, Zhou C, Li S, Ou Yang Z , Huang Y
Received 23 July 2025
Accepted for publication 18 November 2025
Published 25 November 2025 Volume 2025:18 Pages 6179—6183
DOI https://doi.org/10.2147/IDR.S546140
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Professor Chi H. Lee
Yansi Lu,1,2 Xiaoshu Yu,1 Changjing Zhou,1 Shengyi Li,1 Zhaoshun Ou Yang,1 Yuanyuan Huang3
1Department of Infectious Diseases, Baise People’s Hospital, Baise, Guangxi, People’s Republic of China; 2Youjiang Medical College for Nationalities, Baise People’s Hospital, Baise, Guangxi, People’s Republic of China; 3Laboratory PCR Diagnostic Room, Baise People’s Hospital, Baise, Guangxi, People’s Republic of China
Correspondence: Xiaoshu Yu, Department of Infectious Diseases, Baise People’s Hospital, Baise, Guangxi, 533000, People’s Republic of China, Email yyxxss2018@163.com
Abstract: The mpox virus (MPXV) is a zoonotic pathogen that has been causing a worldwide pandemic outbreak since 2022, posing a significant threat to global public health security. During this outbreak, monkeypox has been more prevalent among immunocompromised individuals, particularly those infected with HIV (Human Immunodeficiency Virus). We report a case of a 21-year-old male patient with advanced AIDS in China who developed severe complications, including skin tissue infection, proctitis, and conjunctivitis, following monkeypox infection. Despite early aggressive treatment, the patient ultimately succumbed to infectious shock and multiple organ failure. This case strongly underscores that such patients experience severe skin infections and rapid disease progression, necessitating urgent early recognition and treatment.
Keywords: AIDS, mpox virus, clinical manifestations, differential diagnosis
1Department of Infectious Diseases, Baise People’s Hospital, Baise, Guangxi, People’s Republic of China; 2Youjiang Medical College for Nationalities, Baise People’s Hospital, Baise, Guangxi, People’s Republic of China; 3Laboratory PCR Diagnostic Room, Baise People’s Hospital, Baise, Guangxi, People’s Republic of China
Correspondence: Xiaoshu Yu, Department of Infectious Diseases, Baise People’s Hospital, Baise, Guangxi, 533000, People’s Republic of China, Email yyxxss2018@163.com
Abstract: The mpox virus (MPXV) is a zoonotic pathogen that has been causing a worldwide pandemic outbreak since 2022, posing a significant threat to global public health security. During this outbreak, monkeypox has been more prevalent among immunocompromised individuals, particularly those infected with HIV (Human Immunodeficiency Virus). We report a case of a 21-year-old male patient with advanced AIDS in China who developed severe complications, including skin tissue infection, proctitis, and conjunctivitis, following monkeypox infection. Despite early aggressive treatment, the patient ultimately succumbed to infectious shock and multiple organ failure. This case strongly underscores that such patients experience severe skin infections and rapid disease progression, necessitating urgent early recognition and treatment.
Keywords: AIDS, mpox virus, clinical manifestations, differential diagnosis