111614
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.4 Breast Cancer (Dove Med Press)
- 3.2 Clin Epidemiol
- 2.6 Cancer Manag Res
- 2.9 Infect Drug Resist
- 3.7 Clin Interv Aging
- 5.1 Drug Des Dev Ther
- 3.1 Int J Chronic Obstr
- 6.6 Int J Nanomed
- 2.6 Int J Women's Health
- 2.9 Neuropsych Dis Treat
- 2.8 OncoTargets Ther
- 2.0 Patient Prefer Adher
- 2.2 Ther Clin Risk Manag
- 2.5 J Pain Res
- 3.0 Diabet Metab Synd Ob
- 3.2 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 1.8 Pharmgenomics Pers Med
- 2.0 Risk Manag Healthc Policy
- 4.1 J Inflamm Res
- 2.0 Int J Gen Med
- 3.4 J Hepatocell Carcinoma
- 3.0 J Asthma Allergy
- 2.2 Clin Cosmet Investig Dermatol
- 2.4 J Multidiscip Healthc
已发表论文
中国肝癌患者及其家属对乙型肝炎和肝癌的知识、态度和行为
Authors Deng Q, Chen Y, He M, Fu C, Wu C, Wu S, Liu F , Yin X, Wu Y, Ma K
Received 11 June 2025
Accepted for publication 4 November 2025
Published 25 November 2025 Volume 2025:17 Pages 2873—2891
DOI https://doi.org/10.2147/CMAR.S540633
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Antonella D'Anneo
Qingsong Deng,1,* Ying Chen,1,* Minglian He,1,* Chunchuan Fu,2 Chuanxin Wu,3 Shitao Wu,4 Fenghao Liu,1 Xiubi Yin,1 Yuzhang Wu,5 Kuansheng Ma1
1Army Institute of Hepatobiliary Surgery, the First Affiliated Hospital of Army Medical University, Chongqing, 400038, People’s Republic of China; 2Department of Hepatobiliary Surgery, Xuanhan County People’s Hospital, Xuanhuan, 636150, People’s Republic of China; 3Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People’s Republic of China; 4Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People’s Republic of China; 5Institute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, 400038, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Kuansheng Ma, Email kuanshengma@outlook.com Yuzhang Wu, Email wuyuzhang@yahoo.com
Purpose: This study aims to assess the knowledge, attitudes, and practices (KAP) of liver cancer patients and their family members regarding hepatitis B and liver cancer in hospitals in central and western China.
Patients and Methods: A multicenter cross-sectional survey was conducted on liver cancer patients and their families between February 2023 and August 2024. Data were collected using a validated, self-developed questionnaire.
Results: A total of 810 valid questionnaires were analyzed, with 432 (53.33%) respondents being family members. The mean scores for knowledge, attitude, and practice were 7.19 ± 3.68, 43.71 ± 4.30, and 39.93 ± 6.06, respectively. Multivariate logistic regression identified education (OR = 3.009 for high school/technical school; OR = 6.771 for associate degree or above), hepatitis B diagnosis (OR = 1.530), and duration of liver cancer diagnosis (OR=1.690) as significant predictors of knowledge scores. Positive attitudes were linked to higher knowledge scores (OR=1.212), high school/technical school education (OR=1.831), and a monthly per capita income of 10,000– 20,000 Yuan (OR=2.964). For practices, predictors included higher knowledge scores (OR=1.067), higher attitude scores (OR=1.241), non-disclosure of income (OR=3.311), current alcohol consumption (OR=0.303), and diabetes (OR=2.175).
Conclusion: Liver cancer patients and their family members demonstrated inadequate knowledge but relatively positive attitudes and proactive practices regarding hepatitis B and liver cancer in hospitals in central and western China. This knowledge–practice gap may reflect cultural norms, family support, or public health campaigns, yet improving knowledge remains essential to sustain positive behaviors. Targeted educational interventions should therefore be integrated into clinical and community care. In particular, future interventions should be tailored to address urban–rural disparities and to actively involve family members in supporting patients. These findings provide practical implications for enhancing health literacy, guiding policymaking, and improving counseling strategies to strengthen disease management and prevention.
Keywords: hepatocellular carcinoma, hepatitis B, liver neoplasms, cross-sectional study, patient education
1Army Institute of Hepatobiliary Surgery, the First Affiliated Hospital of Army Medical University, Chongqing, 400038, People’s Republic of China; 2Department of Hepatobiliary Surgery, Xuanhan County People’s Hospital, Xuanhuan, 636150, People’s Republic of China; 3Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People’s Republic of China; 4Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People’s Republic of China; 5Institute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, 400038, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Kuansheng Ma, Email kuanshengma@outlook.com Yuzhang Wu, Email wuyuzhang@yahoo.com
Purpose: This study aims to assess the knowledge, attitudes, and practices (KAP) of liver cancer patients and their family members regarding hepatitis B and liver cancer in hospitals in central and western China.
Patients and Methods: A multicenter cross-sectional survey was conducted on liver cancer patients and their families between February 2023 and August 2024. Data were collected using a validated, self-developed questionnaire.
Results: A total of 810 valid questionnaires were analyzed, with 432 (53.33%) respondents being family members. The mean scores for knowledge, attitude, and practice were 7.19 ± 3.68, 43.71 ± 4.30, and 39.93 ± 6.06, respectively. Multivariate logistic regression identified education (OR = 3.009 for high school/technical school; OR = 6.771 for associate degree or above), hepatitis B diagnosis (OR = 1.530), and duration of liver cancer diagnosis (OR=1.690) as significant predictors of knowledge scores. Positive attitudes were linked to higher knowledge scores (OR=1.212), high school/technical school education (OR=1.831), and a monthly per capita income of 10,000– 20,000 Yuan (OR=2.964). For practices, predictors included higher knowledge scores (OR=1.067), higher attitude scores (OR=1.241), non-disclosure of income (OR=3.311), current alcohol consumption (OR=0.303), and diabetes (OR=2.175).
Conclusion: Liver cancer patients and their family members demonstrated inadequate knowledge but relatively positive attitudes and proactive practices regarding hepatitis B and liver cancer in hospitals in central and western China. This knowledge–practice gap may reflect cultural norms, family support, or public health campaigns, yet improving knowledge remains essential to sustain positive behaviors. Targeted educational interventions should therefore be integrated into clinical and community care. In particular, future interventions should be tailored to address urban–rural disparities and to actively involve family members in supporting patients. These findings provide practical implications for enhancing health literacy, guiding policymaking, and improving counseling strategies to strengthen disease management and prevention.
Keywords: hepatocellular carcinoma, hepatitis B, liver neoplasms, cross-sectional study, patient education