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已发表论文
中国广州妊娠期糖尿病女性身体活动的轨迹及预测因素：一项前瞻性研究
Authors Zhao H, Lan Y, Lin W, Li Z
Received 19 August 2025
Accepted for publication 13 November 2025
Published 25 November 2025 Volume 2025:17 Pages 4755—4767
DOI https://doi.org/10.2147/IJWH.S561747
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Matteo Frigerio
Hui Zhao,1 Yutao Lan,1 Wenxuan Lin,2 Zhiyun Li2
1Department of Nursing, Guangdong Pharmaceutical University, Guangzhou, 510315, People’s Republic of China; 2Department of Nursing, Guangdong Maternal and Child Health Hospital, Guangzhou, 510000, People’s Republic of China
Correspondence: Yutao Lan, Department of Nursing, Guangdong Pharmaceutical University, Jianghai Street No. 283, Haizhu District, Guangzhou, 510315, People’s Republic of China, Tel +86-13710667351, Email lanyutao@gdpu.edu.cn
Purpose: This study analyzed physical activity (PA) trajectories, identified subgroups, and explored their associations in women with gestational diabetes mellitus (GDM).
Methods: From January to November 2024, a longitudinal study was conducted using convenience sampling to recruit women with GDM from a maternal and child health hospital in Guangzhou (China). General information and baseline PA data were collected at diagnosis (24--26 weeks of gestation), and follow-up PA assessments were carried out at 28, 32, and 36 weeks. The Pregnancy Physical Activity Questionnaire (PPAQ) was used to assess PA levels. The latent class growth model (LCGM) identified distinct PA trajectories.
Results: Of the 236 women enrolled, 223 completed follow-up. PA scores increased from T0 to a peak at T1 (median 156.45 MET·h/w, IQR: 113.08– 221.10), then declined to a low at T3 (114.63 ± 47.30 MET·h/w). LCGM identified three trajectory subgroups: high-level reduction (4.04%), moderate-level fluctuation (43.50%), and low-level stable (52.47%). Ordinal logistic regression showed that unemployment (odds ratio (OR): 4.754; 95% confidence interval (CI): 1.878– 12.037) and exercising alone (OR: 2.268; 95% CI: 1.219– 4.225) were significantly associated with subgroup membership (P< 0.05).
Conclusion: PA levels in women with GDM initially rose and then declined, with most sustaining stable low activity. Unemployment and solitary exercise were significant predictors of lower PA trajectories.
Keywords: gestational diabetes mellitus, physical activity, latent class growth model, longitudinal study
1Department of Nursing, Guangdong Pharmaceutical University, Guangzhou, 510315, People’s Republic of China; 2Department of Nursing, Guangdong Maternal and Child Health Hospital, Guangzhou, 510000, People’s Republic of China
Correspondence: Yutao Lan, Department of Nursing, Guangdong Pharmaceutical University, Jianghai Street No. 283, Haizhu District, Guangzhou, 510315, People’s Republic of China, Tel +86-13710667351, Email lanyutao@gdpu.edu.cn
Purpose: This study analyzed physical activity (PA) trajectories, identified subgroups, and explored their associations in women with gestational diabetes mellitus (GDM).
Methods: From January to November 2024, a longitudinal study was conducted using convenience sampling to recruit women with GDM from a maternal and child health hospital in Guangzhou (China). General information and baseline PA data were collected at diagnosis (24--26 weeks of gestation), and follow-up PA assessments were carried out at 28, 32, and 36 weeks. The Pregnancy Physical Activity Questionnaire (PPAQ) was used to assess PA levels. The latent class growth model (LCGM) identified distinct PA trajectories.
Results: Of the 236 women enrolled, 223 completed follow-up. PA scores increased from T0 to a peak at T1 (median 156.45 MET·h/w, IQR: 113.08– 221.10), then declined to a low at T3 (114.63 ± 47.30 MET·h/w). LCGM identified three trajectory subgroups: high-level reduction (4.04%), moderate-level fluctuation (43.50%), and low-level stable (52.47%). Ordinal logistic regression showed that unemployment (odds ratio (OR): 4.754; 95% confidence interval (CI): 1.878– 12.037) and exercising alone (OR: 2.268; 95% CI: 1.219– 4.225) were significantly associated with subgroup membership (P< 0.05).
Conclusion: PA levels in women with GDM initially rose and then declined, with most sustaining stable low activity. Unemployment and solitary exercise were significant predictors of lower PA trajectories.
Keywords: gestational diabetes mellitus, physical activity, latent class growth model, longitudinal study