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已发表论文
青少年抑郁症患者非自杀性自伤风险个体化预测诺模图预测模型的构建
Authors Zhao Q, Zeng L, Hu S, Lei F
Received 18 July 2025
Accepted for publication 18 November 2025
Published 3 December 2025 Volume 2025:21 Pages 2747—2758
DOI https://doi.org/10.2147/NDT.S549935
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Taro Kishi
Qingyan Zhao,1 Lingbin Zeng,2 Shaolun Hu,3 Fenfang Lei1
1School of Nursing of Shaoyang University, Shaoyang, Hunan, 422000, People’s Republic of China; 2Institute office of Shaoyang Brain Hospital, Shaoyang, Hunan, 422000, People’s Republic of China; 3The Psychiatric Clinic of Shaoyang Brain Hospital, Shaoyang, Hunan, 422000, People’s Republic of China
Correspondence: Fenfang Lei, School of nursing of Shaoyang University, Qiliping, Xueyuan Road, Daxiang District, Shaoyang, Hunan, 422000, People’s Republic of China, Tel +8615115981926, Email eruroi3874@sina.com
Objective: To develop a nomogram model for individualized prediction of non-suicidal self-injury (NSSI) risk in adolescent depression patients.
Methods: Clinical data from 270 adolescent depression patients (August 2022–January 2025) were randomly divided into modeling and validation groups. The modeling group was split into NSSI and non-NSSI subgroups based on NSSI occurrence. Logistic regression identified risk factors. R software was used to construct the nomogram, while ROC and DCA evaluated its discrimination and clinical utility.
Results: A total of 189 patients from our hospital were retrospectively selected, among whom 72 patients (38.10%) were identified as having engaged in NSSI behavior within the past year. Disease duration, depression level, childhood abuse, family dysfunction, school bullying, sleep disorder, and Barratt Impulsiveness were significant risk factors (P< 0.05). AUCs were 0.899 (modeling) and 0.954 (validation). H-L tests showed good fit: χ²=7.243 (P=0.721) and χ²=7.010 (P=0.711). The DCA curve indicated high clinical value when probability ranged from 0.05 to 0.97.
Conclusion: Disease course, severity of depression, childhood abuse, dysfunctional family environment during childhood, experiences of school bullying, sleep disorders, and Barratt Impulsiveness Scale scores were identified as influencing factors for NSSI in adolescents with depression. Based on these factors, a nomogram model was constructed, which showed good predictive consistency and high clinical applicability. This model can assist clinicians in identifying high-risk individuals for early prevention. Although the model may help guide interventions to reduce the incidence of NSSI, further validation through rigorously designed implementation studies is still required.
Keywords: teenagers, depression, non suicidal self injury, risk factors, nomogram
1School of Nursing of Shaoyang University, Shaoyang, Hunan, 422000, People’s Republic of China; 2Institute office of Shaoyang Brain Hospital, Shaoyang, Hunan, 422000, People’s Republic of China; 3The Psychiatric Clinic of Shaoyang Brain Hospital, Shaoyang, Hunan, 422000, People’s Republic of China
Correspondence: Fenfang Lei, School of nursing of Shaoyang University, Qiliping, Xueyuan Road, Daxiang District, Shaoyang, Hunan, 422000, People’s Republic of China, Tel +8615115981926, Email eruroi3874@sina.com
Objective: To develop a nomogram model for individualized prediction of non-suicidal self-injury (NSSI) risk in adolescent depression patients.
Methods: Clinical data from 270 adolescent depression patients (August 2022–January 2025) were randomly divided into modeling and validation groups. The modeling group was split into NSSI and non-NSSI subgroups based on NSSI occurrence. Logistic regression identified risk factors. R software was used to construct the nomogram, while ROC and DCA evaluated its discrimination and clinical utility.
Results: A total of 189 patients from our hospital were retrospectively selected, among whom 72 patients (38.10%) were identified as having engaged in NSSI behavior within the past year. Disease duration, depression level, childhood abuse, family dysfunction, school bullying, sleep disorder, and Barratt Impulsiveness were significant risk factors (P< 0.05). AUCs were 0.899 (modeling) and 0.954 (validation). H-L tests showed good fit: χ²=7.243 (P=0.721) and χ²=7.010 (P=0.711). The DCA curve indicated high clinical value when probability ranged from 0.05 to 0.97.
Conclusion: Disease course, severity of depression, childhood abuse, dysfunctional family environment during childhood, experiences of school bullying, sleep disorders, and Barratt Impulsiveness Scale scores were identified as influencing factors for NSSI in adolescents with depression. Based on these factors, a nomogram model was constructed, which showed good predictive consistency and high clinical applicability. This model can assist clinicians in identifying high-risk individuals for early prevention. Although the model may help guide interventions to reduce the incidence of NSSI, further validation through rigorously designed implementation studies is still required.
Keywords: teenagers, depression, non suicidal self injury, risk factors, nomogram