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已发表论文
成人巨大腹膜后成熟畸胎瘤 1 例报告并文献复习
Authors Ren XK , Zhu SG, Xia YZ
Received 26 September 2025
Accepted for publication 26 November 2025
Published 2 December 2025 Volume 2025:17 Pages 5079—5085
DOI https://doi.org/10.2147/IJWH.S569760
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Matteo Frigerio
Xue-kang Ren, Shao-gong Zhu, Yun-zhan Xia
Department of General Surgery, The Fifth Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, 450003, People’s Republic of China
Correspondence: Yun-zhan Xia, The Fifth Clinical Medical College of Henan University of Traditional Chinese Medicine, No. 56 Dongfeng South Road, Zhengdong New District, Zhengzhou, Henan, 450003, People’s Republic of China, Tel +86-6707-9320, Email Xiayunzhan123@163.com
Background: Teratomas usually occur in the gonads. The retroperitoneum is the least common location, which accounts for approximately 4% of primary retroperitoneal tumors and 26% of retroperitoneal teratomas are malignant. Retroperitoneal teratomas occur mainly in childhood, and with a low incidence in adults. Due to its nonspecific clinical and imaging features, the disease is difficult to distinguish from cystadenoma and other diseases, making accurate diagnosis a persistent clinical challenge.
Case Presentation: Here, we present a 65-year-old female patient who was admitted to the hospital due to intermittent right upper abdominal pain for half a month. Preoperative abdominal computed tomography imaging revealed a large mass in the left abdominal cavity, which showed mild enhancement. However, the imaging findings were non-diagnostic, and the nature of the mass could not be determined. Postoperative pathological examination revealed a retroperitoneal mature cystic teratoma. Through close follow-up, the patient achieved a favorable prognosis, and had no local recurrence or distant metastasis 6 years after surgery.
Conclusion: This case highlights the importance of considering teratoma in the differential diagnosis of retroperitoneal tumor and emphasizes the importance of complete surgical resection for the patient’s prognosis, which are critical to preventing misdiagnosis as malignancy and optimizing patient outcomes.
Keywords: retroperitoneal, mature teratoma, massive, adult, prognosis
Department of General Surgery, The Fifth Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, 450003, People’s Republic of China
Correspondence: Yun-zhan Xia, The Fifth Clinical Medical College of Henan University of Traditional Chinese Medicine, No. 56 Dongfeng South Road, Zhengdong New District, Zhengzhou, Henan, 450003, People’s Republic of China, Tel +86-6707-9320, Email Xiayunzhan123@163.com
Background: Teratomas usually occur in the gonads. The retroperitoneum is the least common location, which accounts for approximately 4% of primary retroperitoneal tumors and 26% of retroperitoneal teratomas are malignant. Retroperitoneal teratomas occur mainly in childhood, and with a low incidence in adults. Due to its nonspecific clinical and imaging features, the disease is difficult to distinguish from cystadenoma and other diseases, making accurate diagnosis a persistent clinical challenge.
Case Presentation: Here, we present a 65-year-old female patient who was admitted to the hospital due to intermittent right upper abdominal pain for half a month. Preoperative abdominal computed tomography imaging revealed a large mass in the left abdominal cavity, which showed mild enhancement. However, the imaging findings were non-diagnostic, and the nature of the mass could not be determined. Postoperative pathological examination revealed a retroperitoneal mature cystic teratoma. Through close follow-up, the patient achieved a favorable prognosis, and had no local recurrence or distant metastasis 6 years after surgery.
Conclusion: This case highlights the importance of considering teratoma in the differential diagnosis of retroperitoneal tumor and emphasizes the importance of complete surgical resection for the patient’s prognosis, which are critical to preventing misdiagnosis as malignancy and optimizing patient outcomes.
Keywords: retroperitoneal, mature teratoma, massive, adult, prognosis