111614
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.4 Breast Cancer (Dove Med Press)
- 3.2 Clin Epidemiol
- 2.6 Cancer Manag Res
- 2.9 Infect Drug Resist
- 3.7 Clin Interv Aging
- 5.1 Drug Des Dev Ther
- 3.1 Int J Chronic Obstr
- 6.6 Int J Nanomed
- 2.6 Int J Women's Health
- 2.9 Neuropsych Dis Treat
- 2.8 OncoTargets Ther
- 2.0 Patient Prefer Adher
- 2.2 Ther Clin Risk Manag
- 2.5 J Pain Res
- 3.0 Diabet Metab Synd Ob
- 3.2 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 1.8 Pharmgenomics Pers Med
- 2.0 Risk Manag Healthc Policy
- 4.1 J Inflamm Res
- 2.0 Int J Gen Med
- 3.4 J Hepatocell Carcinoma
- 3.0 J Asthma Allergy
- 2.2 Clin Cosmet Investig Dermatol
- 2.4 J Multidiscip Healthc
已发表论文
归脾胶囊改善失眠疗效及机制的研究进展
Received 8 April 2025
Accepted for publication 24 September 2025
Published 1 December 2025 Volume 2025:18 Pages 7175—7184
DOI https://doi.org/10.2147/IJGM.S532993
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Gauri Agarwal
Shikang Li,1 Xuemei Feng2
1School of Health Economics and Management, Nanjing University of Chinese Medicine, Nanjing, 210023, People’s Republic of China; 2School of Basic Medical Sciences, Shanghai Jiaotong University, Shanghai, 200240, People’s Republic of China
Correspondence: Xuemei Feng, Email fxm0118@163.com
Abstract: Insomnia is a common clinical disorder characterized by difficulty falling asleep or maintaining sleep with daytime irritability or fatigue. The annual prevalence of insomnia symptoms in the global adult population is 35– 50% and the prevalence of insomnia disorders is 12– 20%. Most patients with insomnia cost a lot but fail to receive effective treatment. First-line treatments for insomnia include cognitive-behavioral therapy (CBT-I) and medication, but they both have limitations such as expensive and serious side effects. Traditional Chinese herbal remedies, such as the Guipi capsule, are selected as an alternative strategy of treatment because of more convenient, affordable, and fewer side-effects. Here, we review the potential pathogenesis of insomnia, the pharmacological ingredients of the Guipi capsule, and its effects and mechanisms in treating insomnia.
Keywords: Guipi capsule, insomnia, mechanisms, pathogenesis, pharmacological ingredients
1School of Health Economics and Management, Nanjing University of Chinese Medicine, Nanjing, 210023, People’s Republic of China; 2School of Basic Medical Sciences, Shanghai Jiaotong University, Shanghai, 200240, People’s Republic of China
Correspondence: Xuemei Feng, Email fxm0118@163.com
Abstract: Insomnia is a common clinical disorder characterized by difficulty falling asleep or maintaining sleep with daytime irritability or fatigue. The annual prevalence of insomnia symptoms in the global adult population is 35– 50% and the prevalence of insomnia disorders is 12– 20%. Most patients with insomnia cost a lot but fail to receive effective treatment. First-line treatments for insomnia include cognitive-behavioral therapy (CBT-I) and medication, but they both have limitations such as expensive and serious side effects. Traditional Chinese herbal remedies, such as the Guipi capsule, are selected as an alternative strategy of treatment because of more convenient, affordable, and fewer side-effects. Here, we review the potential pathogenesis of insomnia, the pharmacological ingredients of the Guipi capsule, and its effects and mechanisms in treating insomnia.
Keywords: Guipi capsule, insomnia, mechanisms, pathogenesis, pharmacological ingredients