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已发表论文
关于酒渣鼻治疗的当前趋势与未来展望：文献计量分析
Authors Wang D , Zhang J, Wang B , Gao J, Zhang G
Received 16 September 2025
Accepted for publication 5 December 2025
Published 13 December 2025 Volume 2025:18 Pages 3397—3412
DOI https://doi.org/10.2147/CCID.S568058
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Michela Starace
Dongxue Wang,1– 3 Jinfang Zhang,1– 3 Bin Wang,1– 3 Jiefang Gao,1– 3 Guoqiang Zhang1– 3
1Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050031, People’s Republic of China; 2Subcenter of National Clinical Research Center for Skin and Immune Diseases, Shijiazhuang, Hebei, 050031, People’s Republic of China; 3Hebei Technical Innovation Center for Dermatology and Medical Cosmetology Technology, Shijiazhuang, Hebei, 050031, People’s Republic of China
Correspondence: Guoqiang Zhang, Email 57702800@hebmu.edu.cn
Background: Rosacea involves immune, neurovascular, and microbial factors, but its complex mechanisms are poorly understood, hindering effective treatment development. This study aims to examine research trends and significant contributions in the treatment of rosacea.
Methods: Publications related to rosacea treatment were retrieved from the Web of Science Core Collection (WoSCC). Bibliometric analysis and visualization were performed using VOSviewer, CiteSpace, and the R package “bibliometrix”.
Results: By June 7, 2024, 1389 English-language publications published between 1970 and 2024 were identified for analysis. The leading research countries were the United States (446 articles) and China (149 articles), with the Central South University (95 articles) being the most productive institution. Key journals included Journal of the American Academy of Dermatology (impact factor = 12.8) and the British Journal of Dermatology (impact factor = 11). James Q. Del Rosso was identified as a major contributor (h-index = 20). Keywords cluster analysis revealed five prominent themes: 1) pharmacological treatment and clinical trials, 2) epidemiology and associated risk factors, 3) pathophysiology and pathogenesis, 4) skin barrier function and related dermatoses, and 5) laser and physical therapies. Representative terms of emerging trends include “pathogenesis”, “pathophysiology”, and “standard classification”, suggesting increasing focus on immune dysregulation, neurovascular mechanisms, and microbiome-related pathways. These insights indicate that future rosacea treatment research may shift toward targeted, mechanism-based therapeutic strategies.
Conclusion: This study underscores the dynamic landscape of research in rosacea treatment, synthesizes current areas of emphasis, and forecasts future trends. Future developments in rosacea research may concentrate on integrating precision medicine approaches by linking molecularly defined pathogenic mechanisms with standardized classification systems, thereby facilitating targeted and multidisciplinary treatment strategies.
Keywords: rosacea, treatment, bibliometric analysis, immune dysregulation, quality of life
1Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050031, People’s Republic of China; 2Subcenter of National Clinical Research Center for Skin and Immune Diseases, Shijiazhuang, Hebei, 050031, People’s Republic of China; 3Hebei Technical Innovation Center for Dermatology and Medical Cosmetology Technology, Shijiazhuang, Hebei, 050031, People’s Republic of China
Correspondence: Guoqiang Zhang, Email 57702800@hebmu.edu.cn
Background: Rosacea involves immune, neurovascular, and microbial factors, but its complex mechanisms are poorly understood, hindering effective treatment development. This study aims to examine research trends and significant contributions in the treatment of rosacea.
Methods: Publications related to rosacea treatment were retrieved from the Web of Science Core Collection (WoSCC). Bibliometric analysis and visualization were performed using VOSviewer, CiteSpace, and the R package “bibliometrix”.
Results: By June 7, 2024, 1389 English-language publications published between 1970 and 2024 were identified for analysis. The leading research countries were the United States (446 articles) and China (149 articles), with the Central South University (95 articles) being the most productive institution. Key journals included Journal of the American Academy of Dermatology (impact factor = 12.8) and the British Journal of Dermatology (impact factor = 11). James Q. Del Rosso was identified as a major contributor (h-index = 20). Keywords cluster analysis revealed five prominent themes: 1) pharmacological treatment and clinical trials, 2) epidemiology and associated risk factors, 3) pathophysiology and pathogenesis, 4) skin barrier function and related dermatoses, and 5) laser and physical therapies. Representative terms of emerging trends include “pathogenesis”, “pathophysiology”, and “standard classification”, suggesting increasing focus on immune dysregulation, neurovascular mechanisms, and microbiome-related pathways. These insights indicate that future rosacea treatment research may shift toward targeted, mechanism-based therapeutic strategies.
Conclusion: This study underscores the dynamic landscape of research in rosacea treatment, synthesizes current areas of emphasis, and forecasts future trends. Future developments in rosacea research may concentrate on integrating precision medicine approaches by linking molecularly defined pathogenic mechanisms with standardized classification systems, thereby facilitating targeted and multidisciplinary treatment strategies.
Keywords: rosacea, treatment, bibliometric analysis, immune dysregulation, quality of life