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腹腔镜 - 内镜联合取石术治疗胆总管结石合并胆囊结石时输尿管导管辅助顺行导丝插管的临床结局及安全性:一项回顾性队列研究

 

Authors Shi B, Feng J, Hu P, Lv S, Wang B, Wang Q, Fang Z, Wang A, Zhang W, Zhang F

Received 22 September 2025

Accepted for publication 17 December 2025

Published 8 January 2026 Volume 2026:22 569440

DOI https://doi.org/10.2147/TCRM.S569440

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Garry Walsh

Binyao Shi,1,2,* Jiayuan Feng,1,2,* Peng Hu,1,2 Shangdong Lv,1,2 Binfeng Wang,1,2 Qi Wang,1,2 Zheping Fang,1,2 Aidong Wang,2,3 Wenlong Zhang,1,2 Fabiao Zhang1,2 

1Department of Hepatobiliary Surgery, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou, Zhejiang Province, 317000, People’s Republic of China; 2Key Laboratory of Minimally Invasive Techniques & Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou, Zhejiang Province, 318000, People’s Republic of China; 3Department of Hepatobiliary Surgery, Enze Hospital, Wenzhou Medical University, Taizhou, Zhejiang Province, 318000, People’s Republic of China

*These authors contributed equally to this study

Correspondence: Fabiao Zhang, Department of Hepatobiliary Surgery, Taizhou Hospital of Zhejiang Province,Wenzhou Medical University, No. 150 of Ximen Street, Linhai City, Taizhou, Zhejiang Province, 317000, People’s Republic of China, Tel +86 13706760105, Email fabiao_zhang@126.com Wenlong Zhang, Department of Hepatobiliary Surgery, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, No. 150 of Ximen Street, Linhai City, Taizhou, Zhejiang Province, 317000, People’s Republic of China, Tel +86 15168614715, Email zhangwenlong_zwl@126.com

Background and Purpose: The laparoscopic-endoscopic rendezvous procedure, which integrates laparoscopic cholecystectomy with intraoperative endoscopic retrograde cholangiopancreatography (ERCP), is an established therapeutic strategy for patients with cholelithiasis and concomitant choledocholithiasis. This study evaluated the impact of ureteral catheter-assisted antegrade guidewire intubation on the procedural success rate and duration of the rendezvous technique, with additional assessment of safety and clinical efficacy.
Methods: Clinical data were retrospectively analyzed from patients with cholelithiasis and concomitant choledocholithiasis who underwent laparoscopic cholecystectomy at the South Campus of Taizhou Hospital (Enze Hospital), Zhejiang Province, between May 2019 and December 2022. A total of 116 patients were assigned to either a control group or an intervention group in which ureteral catheter-assisted guidewire insertion was employed.
Results: The success rate of antegrade guidewire intubation was 98.3% in the intervention group, compared to 91.2% in the control group. The intervention group demonstrated a statistically significant reduction in guidewire insertion time (p < 0.05). No statistically significant differences were observed between groups in terms of intraoperative hospitalization costs, total hospitalization duration, postoperative serum amylase levels or postoperative hospitalization duration (p > 0.05). The total operative duration tended to be lower but did not reach statistical significance in the intervention group compared to the control group, with a p-value of 0.054. No cases of postoperative bile leakage were reported. In the control group, the incidence of acute pancreatitis was 2%, and the incidence of hyperamylasemia was 28.8%. In the intervention group, hyperamylasemia occurred in 25.9% of cases, with no reported instances of acute pancreatitis. Additionally, one patient in the control group developed a pulmonary embolism, and two patients developed ascites accompanied by fever.
Conclusion: The use of ureteral catheter-assisted antegrade guidewire intubation during the laparoscopic-endoscopic rendezvous procedure appears to be a safe and clinically effective approach for managing cholelithiasis and concomitant choledocholithiasis. This technique is associated with a high success rate of guidewire realignment, reduced procedural duration, and a lower incidence of procedure-related complications.

Keywords: common bile duct stones, gallbladder stones, rendezvous technology, ureteral catheter, zebra guidewire antegrade intubation