论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
Authors Wang Y, Yang JX
Received 25 September 2018
Accepted for publication 13 November 2018
Published 7 December 2018 Volume 2018:10 Pages 6803—6813
DOI https://doi.org/10.2147/CMAR.S188087
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Andrew Yee
Peer reviewer comments 2
Editor who approved publication: Professor Kenan Onel
Abstract: Endometrial
cancer (EC) is the most common malignant tumor of the female reproductive tract
in developed countries and the second most common gynecologic malignancy in
China. Although EC is most often diagnosed in postmenopausal women, the
increase in obesity rates and other lifestyle changes has been accompanied by
an increase in the prevalence of EC among younger women. Approximately 4% of
patients are diagnosed before the age of 40 years and before having given
birth. Such patients may have a strong desire to preserve their fertility
despite oncologic risks and thus may be reluctant to undergo standard treatment
for EC, which includes hysterectomy, bilateral salpingo-oophorectomy, and
surgical staging. Therefore, more conservative treatment approaches may need to
be discussed, along with their associated oncologic and reproductive outcomes.
In fact, various studies have confirmed the effectiveness and safety of
conservative treatment in EC. This review aimed to provide a concise yet
informative overview of the current status of fertility-preserving treatment
for EC in China, as well as to summarize the latest and ongoing research
efforts in this area.
Keywords: endometrial
cancer, conservative treatment, Chinese, fertility
