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槐耳 (Trametes robiniophila Murr) ：一种具有显著抗肿瘤作用的中药
Authors Pan J, Yang C, Jiang Z, Huang J
Received 2 November 2018
Accepted for publication 14 January 2019
Published 14 February 2019 Volume 2019:11 Pages 1541—1549
DOI https://doi.org/10.2147/CMAR.S193174
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Colin Mak
Peer reviewer comments 4
Editor who approved publication: Dr Ahmet Emre Eskazan
摘要：槐耳是一种重要的药用真菌，广泛应用于抗肿瘤治疗。越来越多的证据显示，槐耳的抗肿瘤作用主要体现在两个方面——即对肿瘤细胞的直接作用以及调节免疫功能的间接作用。大量实验证明，槐耳能通过多种信号通路有效抑制肿瘤细胞生长，促进肿瘤细胞死亡，抑制肿瘤血管生成及转移。此外，槐耳能增强 CD4+ T细胞及NK细胞的数量和功能，调节巨噬细胞的极化，增强机体免疫功能。本文对槐耳的抗肿瘤作用、机制以及应用进行了综述。
Keywords: Huaier,
cancer, anti-tumor therapy, traditional Chinese medicine, adjuvant
