德孚在中国

108605

论文已发表

提 交 论 文


注册即可获取德孚的最新动态

注 册



IF 收录期刊





更多详情 >>





QR Code

已发表论文

同期多原发肺癌的诊断和治疗 - 病例报告

 

Authors Bao Y, Wu J, Zhang J, Yu Y

Received 9 August 2018

Accepted for publication 21 January 2019

Published 29 May 2019 Volume 2019:12 Pages 4281—4285

DOI https://doi.org/10.2147/OTT.S183319

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Andrew Yee

Peer reviewer comments 3

Editor who approved publication: Dr William Cho

Abstract: The incidence of synchronous multiple primary lung cancer (SMPLC) has been increased in recent years. Because of a variance in clinical management and outcome, it is important to distinguish SMPLC from a primary tumor with intrapulmonary metastases. Here, we reported a diagnosis and treatment procedure regarding a case of a 58‐year‐old woman who presented with synchronous multiple tumor lesions in separate lungs. Using a next generation sequencing technology, a discordant EGFR gene profile from the separate lungs was revealed for this patient. After standard treatment procedures, the therapeutic effects were evaluated by response evaluation criteria in solid tumors (RECIST). This case shows an essential role in the combination of molecular features, together with pathological analysis, during the management of SMPLC, but challenges still required considering during dealing the cases of SMPLC.
Keywords: lung adenocarcinoma, SMPLC, genetic features, EGFR

Figure 1 Chest computed tomography (CT) scans were performed and images were recorded prior to...


Download Article[PDF]