Aim: The aim of this study was to characterize curcumin (CUR)-loaded CD133 aptamer A15 liposomes for their antitumor activity in vitro and in vivo.
Methods: The modified CUR liposomes were prepared by the thin-film hydration technique.
Results: The particles showed spherical shape under electron microscopy with sizes 
Conclusion: These results indicate that A15 modified CUR liposomes are a promising candidate for antitumor drug delivery.
Keywords: CD133 aptamers, curcumin, prostate cancer, liposomes, cell viability, cellular internalization, in vivo evaluation