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一名银屑病患者在依那西普治疗期间发生继发性全身性皮肤粘蛋白病
Authors Zhou X , Mubanga D, Chen Z, Bi X
Received 29 March 2022
Accepted for publication 17 May 2022
Published 31 May 2022 Volume 2022:15 Pages 987—992
DOI https://doi.org/10.2147/CCID.S368390
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Jeffrey Weinberg
Abstract: Cutaneous mucinosis is a rare disease that manifests as an excessive accumulation of mucin in the skin that forms waxy papules or plaques. We report a case of a 44-year-old male psoriatic patient who developed generalized cutaneous mucinosis after 11 months of biological treatment. The patient had a history of psoriasis for 20 years and had been treated with narrow-band UVB phototherapy, methotrexate, or acitretin intermittently. He was started on etanercept after he was diagnosed with psoriatic arthritis, and 11 months later, he complained of swelling in his extremities and myxoid cysts on his fingers. Etanercept was then discontinued due to loss of efficacy and widespread skin lesions. However, the lesions subsided spontaneously after 6 months without specific systemic treatment.
Keywords: etanercept, cutaneous mucinosis, psoriasis, biological therapy