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与腹水和 CA125 升高相关的卵巢 Struma:两病例报告和文献回顾
Authors Wang S , He X, Yang H , Chen L
Received 27 June 2022
Accepted for publication 25 August 2022
Published 7 September 2022 Volume 2022:14 Pages 1291—1296
DOI https://doi.org/10.2147/IJWH.S379128
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Elie Al-Chaer
Abstract: Struma ovarii is a rare variety of specialized monodermal mature ovarian teratoma, it is composed predominantly of thyroid tissue. Ascites is present in one third of patients. The combination of struma ovarii, marked ascites and elevated CA125 is a rare condition, which may mimic ovarian cancer. We described two cases presenting with pelvic mass, ascites and elevated serum CA125 levels, frozen section and final pathology turned out to be struma ovarii. Ascites disappeared and the level of CA125 returned to normal level after operation. One of the cases was associated with pleural effusion, leading to a condition called pseudo-Meigs’ syndrome. Then we reviewed the related literatures to explore the possible mechanism of ascites and pleural effusion, the reason of CA125 elevation and imaging manifestations of struma ovarii. In conclusion, struma ovarii should be considered in the differential diagnosis preoperatively, when presented with pelvic mass, ascites and an elevated CA125 level.
Keywords: struma ovarii, ascites, CA125, case report, pseudo-Meigs’ syndrome