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一例副肿瘤综合征诱发溃疡性结肠炎?
Authors Zhang T, Pan ZB, Tong WJ, Zhou YL, Cheng Y, Jin DQ, Qi SQ, Zhang ZQ
Received 25 April 2023
Accepted for publication 1 August 2023
Published 8 August 2023 Volume 2023:16 Pages 3319—3327
DOI https://doi.org/10.2147/JIR.S418733
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Ning Quan
Background: Paraneoplastic syndromes often cause endocrine, neurological, cutaneous, and hematologic pathologies, and cases with digestive symptoms as prominent cases are rare.
Case Description: A 1-year-old child admitted to the emergency department with severe abdominal distension was later diagnosed with sacrococcygeal yolk cystoma with ulcerative colitis. After symptomatic management, surgical removal of the tumor, and JEB chemotherapy, the symptoms of ulcerative colitis disappeared completely. After 7 years of follow-up, the child grew and developed well, and there was no recurrence of tumor and ulcerative colitis.
Conclusion: Yolk sac tumor with ulcerative colitis is a rare paraneoplastic syndrome with complex clinical manifestations.
Keywords: children, paraneoplastic syndrome, toxic megacolon, ulcerative colitis, yolk sac tumor