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甲状腺功能减退和腹泻婴儿的溶没食子链球菌巴氏亚种脑膜炎
Authors Li J , Yan C, Wei D, Gong X
Received 1 July 2023
Accepted for publication 31 August 2023
Published 14 September 2023 Volume 2023:16 Pages 6217—6223
DOI https://doi.org/10.2147/IDR.S425637
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Prof. Dr. Héctor M Mora-Montes
Abstract: Streptococcus gallolyticus subspecies pasteurianus , formerly classified as S. bovis biotype II/2 until 2003, is a rare cause of infant meningitis. Over the past 2 decades, only a few individual case reports and limited case series exist in the English-language literature. Moreover, the pathogenesis of S. gallolyticus subsp. pasteurianus meningitis in infants is unclear. Here we report a case of meningitis in a 6-week-old infant with hypothyroidism and preceding diarrhea. In this case, S. gallolyticus was cultured from cerebrospinal fluid, and then S. gallolyticus subspecies pasteurianus was identified by metagenomic next-generation Sequencing. The infant recovered uneventfully after a 4-week antibiotic course with ceftriaxone and vancomycin. Then combined with the literature of S. gallolyticus subsp. pasteurianus meningitis in infants, we discuss the possible etiology.
Keywords: Streptococcus gallolyticus subsp. pasteurianus , infant, meningitis, hypothyroidism, diarrhea