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植物源类囊泡纳米颗粒在炎症性疾病中的研究进展
Authors Tan X , Xu Y , Zhou S , Pan M , Cao Y, Cai X, Zhao Q, Zhao K
Received 25 May 2023
Accepted for publication 20 September 2023
Published 29 September 2023 Volume 2023:16 Pages 4363—4372
DOI https://doi.org/10.2147/JIR.S421124
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Ning Quan
Abstract: All humans are universally affected by inflammatory diseases, and there is an urgent need to identify new anti-inflammatory drugs with good therapeutic benefits and minimal side effects to the organism. Recently, it has been found that plant-derived vesicle-like nanoparticles (PDVLNs) have good biocompatibility, with their active ingredients exhibiting good therapeutic effects on inflammation. They can also be used as drug carriers for targeted delivery of anti-inflammatory drugs. Therefore, PDVLNs represent a popular research area for novel anti-inflammatory drugs. This paper details the origin, biological functions, isolation and purification, and identification of PDVLNs, as well as the therapeutic effects of their intrinsic bioactive components on inflammatory diseases. It also introduces their targets as drug carriers to facilitate the development and application of PDVLNs anti-inflammatory drugs.
Keywords: plant, vesicle-like nanoparticles, inflammation, inflammatory diseases