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Authors Gu H, Deng X, Lv Y, Chen Q, Yu W
Received 24 June 2018
Accepted for publication 2 October 2018
Published 27 December 2018 Volume 2019:12 Pages 151—158
DOI https://doi.org/10.2147/JPR.S178118
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Justinn Cochran
Peer reviewer comments 2
Editor who approved publication: Dr Michael Ueberall
Purpose: This
study aimed to investigate the relationship of preoperative chronic pain and
postoperative cognitive dysfunction
(POCD) in non-elderly patients who underwent arthroscopic surgery.
Materials and methods: The pain
intensity was estimated using visual analog scale, and the cognitive function
was assessed by Syndrom Kurz Test. The effects of preoperative chronic pain on
the cognitive scales were comparatively studied between the patients of
observational group (OG, with chronic pain) and control group (CG, without
chronic pain) pre- and postoperatively, and followed up for 3 months.
Results: A total
of 57 non-elderly patients completed the study. Twenty-five patients (44%) with
preoperative chronic pain were assigned to OG and 32 patients (56%) without
chronic pain were assigned to CG. Preoperation chronic pain impaired the
attention ability before surgery and caused less recovery of attention and memory
abilities from 24 hours to 3 months after the surgery. Surgery procedures
improved the attention and memory abilities and impaired the ability of
numerical ability in CG patients. A postoperative pain relief in OG patients
caused more recovery of cognition in addition to surgery procedure-mediated
cognitive recovery. The incidence of POCD was ~3.5% and temporary at 24 hours
after surgery, and disappeared at 2 weeks, 6 weeks and 3 months after the
surgery.
Conclusion: The
incidence of POCD in non-elderly population who underwent arthroscopic surgery
was low. Surgery improved the abilities of attention and memory, and impaired
the ability of counting. The preoperative chronic pain distracted the attention
before surgery, and reduced the recovery of attention and memory abilities
during the follow-up period after the surgery in non-elderly patients.
Keywords: cognition
dysfunction, chronic pain, non-elderly population