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女性血糖和血红蛋白 A1c 水平与尿失禁的关系
Authors Liu N, Xing L, Mao W, Chen S, Wu J, Xu B, Chen M
Received 15 June 2021
Accepted for publication 21 July 2021
Published 31 July 2021 Volume 2021:14 Pages 4105—4116
DOI https://doi.org/10.2147/IJGM.S324332
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 4
Editor who approved publication: Dr Scott Fraser
Objective: The purpose of this study was to evaluate the associations between blood glucose and hemoglobin A1c (HbA1c) levels with the degree of stress urinary incontinence (SUI) and urgency urinary incontinence (UUI) in women.
Methods: We conducted a cross-sectional study of female participants in the National Health and Nutrition Examination Survey (NHANES) database between 2007 and 2012. Univariate and multivariate logistic regressions were used to assess the relationship between blood glucose and HbA1c levels and the degree of SUI and UUI.
Results: A total of 3821 participants were enrolled in the study, of whom 2421 (63.4%) had no SUI, 1133 (29.7%) had monthly SUI, 267 (7.0%) had weekly SUI; 2883 (75.5%) had no UUI, 735 (19.2%) had monthly UUI, 203 (5.3%) had weekly UUI. The levels of blood glucose and HbA1c were positively correlated with SUI and UUI, and increased with increasing degree of UUI. Multivariate logistic regression showed that there was a positive association between blood HbA1c level and degree of SUI.
Conclusion: Our study found that blood glucose and HbA1c levels can be used as indicators of SUI and UUI severity in women.
Keywords: blood glucose, hemoglobin A1c, national health and nutrition examination survey, stress urinary incontinence, urgency urinary incontinence