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纳米脂质体在肝癌诊治中的研究进展
Authors Li Y, Zhang R , Xu Z, Wang Z
Received 14 November 2021
Accepted for publication 26 January 2022
Published 26 February 2022 Volume 2022:17 Pages 909—925
DOI https://doi.org/10.2147/IJN.S349426
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Farooq A. Shiekh
Abstract: The mortality rate of liver cancer is gradually increasing worldwide due to the increasing risk factors such as fatty liver, diabetes, and alcoholic cirrhosis. The diagnostic methods of liver cancer include ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI), among others. The treatment of liver cancer includes surgical resection, transplantation, ablation, and chemoembolization; however, treatment still faces multiple challenges due to its insidious development, high rate of recurrence after surgical resection, and high failure rate of transplantation. The emergence of liposomes has provided new insights into the treatment of liver cancer. Due to their excellent carrier properties and maneuverability, liposomes can be used to perform a variety of functions such as aiding in imaging diagnoses, combinatorial therapies, and integrating disease diagnosis and treatment. In this paper, we further discuss such advantages.
Keywords: liver targeting, nanotherapeutics, nanocarriers, multimodal imaging, nanomedicine, diagnostic treatment integration