已发表论文

全膝关节置换术后关节周围感染的两阶段翻修中关节间隔物的疗效比较:全骨水泥间隔物与灭菌再植金属聚乙烯间隔物

 

Authors Fei Z, Zhang Z, Wang Y, Zhang H, Xiang S

Received 31 December 2021

Accepted for publication 16 March 2022

Published 24 March 2022 Volume 2022:15 Pages 3293—3301

DOI https://doi.org/10.2147/IJGM.S354808

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 4

Editor who approved publication: Dr Scott Fraser

Purpose: Two-stage revision is the most common treatment for periprosthetic joint infection (PJI) following total knee arthroplasty (TKA). Few studies have compared the clinical efficacy of different articulating spacers. This study compared the outcomes of all-cement articulating spacers and sterilized replanted metal-polyethylene articulating spacers for PJI following TKA.
Patients and Methods: In this retrospective observational study, 47 patients who received two-stage revision for PJI following TKA between 2006 and 2020 in our hospital were included. Patients were categorized as receiving an all-cement articulating spacer or a sterilized replanted metal-polyethylene articulating spacer in exclusion. Data on demographics, surgical information, and outcomes were collected in 2021.
Results: Forty-seven spacers were identified: all-cement spacer was noted in 23 patients and sterilized replanted spacer in 24. Patients in the all-cement spacer group had shorter operation time (155.87 ± 33.12 vs 189.79 ± 51.21 min; P = 0.0102) and less blood loss (845.22 ± 525.92 vs 1114.50 ± 547.81 mL; P = 0.0427) in exclusion. Patients in the sterilized replanted spacer group had superior interval range of motion (ROM; 61.00 ± 31.94° vs 31.75 ± 33.38°; P = 0.0072), postoperative ROM (85.00 ± 11.11° vs 77.37 ± 9.18°; P = 0.0329) as compared to all-cement spacers, but there was no difference in infection control between 2 groups.
Conclusion: The two types of spacers had no difference in the reinfection rate, indicating that both articulating spacers are safe and effective for 2-stage revision. Considering ROM of knee joint, bone loss and cost, sterilized replanted metal-polyethylene spacers are preferred in the treatment of PJI.
Keywords: total knee arthroplasty, periprosthetic joint infection, articulating spacer