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融合整晚特征和去饱和片段并结合特征提取的睡眠呼吸障碍事件级筛查
Authors Liu R , Li C, Xu H, Wu K, Li X, Liu Y , Yuan J, Meng L, Zou J, Huang W , Yi H , Sheng B, Guan J, Yin S
Received 22 December 2021
Accepted for publication 3 May 2022
Published 17 May 2022 Volume 2022:14 Pages 927—940
DOI https://doi.org/10.2147/NSS.S355369
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Prof. Dr. Ahmed BaHammam
Purpose: Misdiagnosis and missed diagnosis of sleep-disordered breathing (SDB) is common because polysomnography (PSG) is time-consuming, expensive, and uncomfortable. The use of recording methods based on the oxygen saturation (SpO2) signals detected by wearable devices is impractical and inaccurate for extracting signal features and detecting apnoeic events. We propose a method to automatically detect the apnoea-based SpO2 signal segments and compute the apnoea–hypopnea index (AHI) for SDB screening and grading.
Patients and Methods: First, apnoea-related desaturation segments in raw SpO2 signals were detected; global features were extracted from whole night signals. Then, the SpO2 signal segments and global features were fed into a bi-directional long short-term memory convolutional neural network model to identify apnoea-related and non-apnoea-related events. The apnoea-related segments were used to assess the AHI.
Results: The model was trained on 500 individuals and tested on 8131 individuals from two public hospitals and one private centre. In the testing data, the classification accuracy for apnoea-related segments was 84.3%. Individuals with SDB (AHI 15) were identified with a mean accuracy of 88.95%.
Conclusion: Using automatic SDB detection based on SpO2 signals can accurately screen for SDB.
Keywords: sleep apnea hypopnea syndrome, AHI, SDB severity classification, Bi-LSTM-CNN, desaturation events