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中国东南部 40 岁及以上成人慢性阻塞性肺疾病患病率及相关危险因素:2019-2020 年横断面研究
Authors Chen J , Yin Y, Zhang Y, Lin X, Chen T, Yang Z, Wang D, Zhong W
Received 14 June 2022
Accepted for publication 9 September 2022
Published 17 September 2022 Volume 2022:17 Pages 2317—2328
DOI https://doi.org/10.2147/COPD.S377857
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Richard Russell
Purpose: Chronic obstructive pulmonary disease (COPD) is one of many major public health problems in China, and its prevalence and associated risk factors in the southeast of China need to be determined to facilitate disease control and prevention.
Methods: A multistage stratified cluster sampling method was used to select 5486 participants aged ≥ 40 years from nine COPD monitoring districts in Fujian Province during 2019– 2020. Participants were interviewed using a laptop-based questionnaire and underwent pulmonary function tests. COPD was diagnosed according to the 2019 Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria.
Results: Final analysis was conducted using data from 4999 participants with qualified post-bronchodilator results. The prevalence of COPD was 11.6% (95% confidence interval [CI]: 10.5– 12.7). Risk factors for COPD in the logistic regression model were being male (odds ratio [OR] = 2.83, 95% CI: 2.01– 3.98), > 70 years old (OR = 16.16, 95% CI: 8.14– 32.08), having a low body mass index (BMI) (OR = 1.81, 95% CI: 1.13– 2.89), parental history of respiratory disease (OR = 1.78, 95% CI: 1.50– 2.10), being a current (OR = 2.82, 95% CI: 1.83– 4.36) or former (OR = 2.47, 95% CI: 1.45– 4.19) smoker, and indoor exposure to biomass (OR = 1.28, 95% CI: 1.05– 1.58).
Conclusion: The estimated prevalence of COPD in southeast China is high. COPD was strongly associated with sex, aging, a low BMI, parental history of respiratory diseases, smoking, and indoor exposure to biomass in adults aged ≥ 40 years. The government should urgently implement comprehensive measures to reduce the risk factors for COPD.
Keywords: COPD, logistic models, biomass, public health, smoking, surveys and questionnaires