Objective: The prevalence of hyperuricemia appears to be high worldwide. We aimed to explore the interaction between harmful alcohol use and tea consumption on hyperuricemia.
Methods: This study recruited 22,449 Han residents based on the data from the China Multi-Ethnic Cohort (CMEC) study, Chongqing province, to have a face-to-face electronic questionnaire, physical examination, and clinical laboratory tests. The difference in hyperuricemia between the different populations was compared by the Chi-square test. The interaction between harmful alcohol use and tea consumption was analyzed by the multivariate logistic regression model.
Results: Amongst 22,449 participants, the mean age was 51.5± 11.8 years, and 46.83% of them were males. The proportion of harmful alcohol use, tea consumption, and harmful alcohol use and tea consumption were 14.01%, 21.01%, and 6.54%, respectively. Multivariate logistic regression showed that the odds ratio (OR) of harmful alcohol use and tea consumption (OR=2.21, 95% CI: 1.58– 3.10) was greater than that of harmful alcohol use (OR=1.63, 95% CI:1.17– 2.27) and tea consumption (OR=1.34, 95% CI:1.10– 1.63). Among males, the results were similar (harmful alcohol use and tea consumption: OR=2.02, 95% CI: 1.43– 2.84; harmful alcohol use: OR=1.61, 95% CI: 1.14– 2.27; tea consumption: OR=1.28, 95% CI: 1.05– 1.57). However, among females, the odds ratio of harmful alcohol use and tea consumption (OR=15.50, 95% CI: 1.36– 176.50) was more than 10 times than that of only harmful alcohol use (OR=1.55, 95% CI: 0.42– 5.69) or tea consumption (OR=1.22, 95% CI: 0.52– 2.82).
Conclusion: The interaction of harmful alcohol use and tea consumption was a positive risk for hyperuricemia in Han residents aged 30– 79 years in China.
Keywords: hyperuricemia, tea consumption, harmful alcohol use, interaction, Han residents