已发表论文

线粒体自噬、炎症小体及其相互作用在肾脏疾病中的研究进展

 

Authors Wang Y , Song D , Tang L

Received 21 December 2022

Accepted for publication 17 March 2023

Published 5 April 2023 Volume 2023:16 Pages 1457—1469

DOI https://doi.org/10.2147/JIR.S402290

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Ning Quan

摘要:线粒体自噬通过调节自噬小体特异性吞噬、降解和清除受损线粒体,是线粒体质量控制的重要机制,在细胞损伤和疾病发生进展中发挥关键作用。炎症小体是近些年来新发现的重要炎症相关因子,参与细胞固有免疫及炎症反应,在肾脏疾病中有重要作用。基于目前的研究进展,我们综述了线粒体自噬、炎症小体及二者的交互作用在肾脏疾病中的研究进展。
Keywords: mitophagy, inflammasomes, kidney diseases, acute kidney injury, chronic kidney disease, diabetic kidney disease