已发表论文

肾移植患者肺类圆线虫病引起的大量气道出血

 

Authors Zhu L , Zhang H, Fang J, Xiao S, Xiong F, Deng C , Yang Q, Fu C, Pan Q, Zhao H 

Received 29 October 2023

Accepted for publication 26 December 2023

Published 3 January 2024 Volume 2024:17 Pages 1—7

DOI https://doi.org/10.2147/IMCRJ.S442535

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Ronald Prineas

Introduction: We report a fatal case of massive airway bleeding caused by pulmonary strongyloidiasis in a patient with a transplanted kidney.
Case Presentation: A 47-year-old male, regularly taking immunosuppressants post-kidney transplant, visited our hospital with symptoms of abdominal bloating, nausea, and emesis persisting for three days. After hospitalization, he developed a cough, hemoptysis, and respiratory failure. Sputum analysis confirmed an infestation with Strongyloides stercoralis. Despite receiving albendazole therapy and bronchoscopic management for bronchial hemorrhage, the patient ultimately died due to acute respiratory and circulatory collapse triggered by severe airway bleeding.
Conclusion: Patients undergoing immunosuppressive therapy following kidney transplantation are at increased risk for disseminated strongyloidiasis. Consequently, infectious disease screening prior to transplantation, along with essential preventive pharmacotherapy, is of paramount importance.

Keywords: strongyloides stercoralis, kidney transplantation, airway bleeding, disseminated infection