Xiaoyue Feng,* Jianli Shang,* Zhengping Gu, Xingyi Luo, Yong Chen, Youting Liu

Product Research & Development Center, Beijing Underproved Medical Technology Co., LTD, Beijing, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Youting Liu, Product Research & Development Center, Beijing Underproved Medical Technology Co., LTD, Beijing, 102699, People’s Republic of China, Tel +86 1 851 025 6963, Email YtLiu.adpt@outlook.com

Abstract: Lactic acid is the most widely occurring natural organic acid in nature. It not only exhibits mild and safe properties but also possesses multiple physiological activities, such as antibacterial effects, immune regulation, and promotion of wound healing, making it one of the most popular chemical peeling agents. Chemical peels are commonly used in the field of aesthetic dermatology as a non-invasive therapeutic approach. This research aims to provide valuable references for clinical dermatologists by summarizing the characteristics of lactic acid, elucidating its mechanism of action in peeling, and investigating the clinical applications of this compound. Furthermore, it anticipates the potential for lactic acid to be the most suitable chemical peeling agent for Chinese skin.

Keywords: lactic acid, physiological activities, clinical applications, Chinese skin