Dingbin Yang,1,2 Yu Mao,3 Lu Peng,2 Shuqiong Huang,2 Lijun Zhou,2 Changqiang Li1 

1Department of Dermatology, the Affiliated Hospital, Southwest Medical University, Luzhou, 646000, People’s Republic of China; 2Department of Dermatology, People’s Hospital of Leshan, Leshan, 614000, People’s Republic of China; 3Department of Pathology, People’s Hospital of Leshan, Leshan, 614000, People’s Republic of China

Correspondence: Changqiang Li, Department of Dermatology, the Affiliated Hospital, Southwest Medical University, Luzhou, 646000, People’s Republic of China, Email lcq-1973@163.com

Abstract: Keratoacanthoma (KA) is a papule, plaque, or nodule in an exposed area, with a crater-like horn plug in the center. Multiple KAs are rare disorders, especially when the lesions are agglomerated together. Herein, we report a case of 65-year-old man who presented with four red nodules of different sizes on the right side of the chest. The lesions were clustered, with central keratotic cores, similar in appearance to a four-leaf clover. The nodules were completely removed by excisional surgery and the diagnosis of Agglomerate KAs was made based on clinical and pathological results. A 6-year follow-up found no recurrence.

Keywords: agglomerate keratoacanthomas, four-leaf clover