Zonglei Chong,1,* Xiaoqian Yang,1,* Xiaoxiao Peng,2 Qiang Zong,3 Hongxing Li,3,* Yilei Xiao1,* 

1Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China; 2Dongying District People’s Hospital, Dongying, Shandong, People’s Republic of China; 3Shengli Oilfield Central Hospital, Dongying, Shandong, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Yilei Xiao, Department of Neurosurgery, Liaocheng People’s Hospital, No. 67 Dongchang West Road, Dongchangfu District, Liaocheng, Shandong Province, 252000, People’s Republic of China, Email yileixiao@163.com Hongxing Li, Department of Neurosurgery, Shengli Oilfield Central Hospital, No. 31 Jinan Road, Dongying, Shandong Province, 257000, People’s Republic of China, Email lihongxing159@126.com

Abstract: We report the case of a 53-year-old man who was diagnosed with Holmes tremor and underwent deep brain stimulation of the ventro-intermediate thalamic nucleus and posterior subthalamic area. We assessed the patients’ tremor with the Fahn-Tolosa-Marin Tremor Rating Scale at 1, 3, 6, 12 and 24 months after deep brain stimulation. Deep brain stimulation relieved the patient’s tremor during the 24-month follow-up period.

Keywords: deep brain stimulation, Holmes’ tremor, posterior subthalamic area, the ventro-intermediate thalamic nucleus, ventro-intermediate thalamic nucleus