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罗哌卡因用于肋锁臂丛-颈丛联合阻滞对肱骨骨折术后膈肌麻痹的影响:一项前瞻性单中心队列研究

 

Authors Zhu M , Yuan L , Mei Z , Sheng Z , Ge Y, Zhang L , Liu G

Received 5 August 2024

Accepted for publication 16 November 2024

Published 28 November 2024 Volume 2024:18 Pages 5473—5483

DOI https://doi.org/10.2147/DDDT.S483358

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Anastasios Lymperopoulos

Miao Zhu,1 Liyong Yuan,1 Zhong Mei,2 Zhimin Sheng,3 Yeying Ge,1 Long Zhang,1 Guanyi Liu4 

1Department of Anesthesiology, Ningbo No.6 hospital, Ningbo University School of Medicine, Ningbo, Zhejiang, People’s Republic of China; 2Department of Anesthesiology, Zhejiang Xiaoshan Hospital, Hangzhou, People’s Republic of China; 3Department of Anesthesiology, Wenling Maternity and Child Health Care Hospital, Taizhou, People’s Republic of China; 4Department of Orthopedics, Ningbo No.6 hospital, Ningbo University School of Medicine, Ningbo, Zhejiang, People’s Republic of China

Correspondence: Guanyi Liu, Department of Orthopaedics, Ningbo No.6 hospital, Zhongshan East Road 1059, Ningbo, Zhejiang, 315040, People’s Republic of China, Email 18906628697@163.com

Background: The brachial plexus block is conducive to providing postoperative analgesia for patients with humeral fractures. The commonly used brachial plexus block techniques have a high incidence rate of hemidiaphragmatic paralysis (HDP), which may lead to respiratory problems. The combined costoclavicular brachial plexus - cervical plexus blocks (CCB-CPBs) had demonstrated favorable analgesic effects and had reduced the incidence of HDP in shoulder surgeries. However, the clinical experience regarding CCB-CPBs is rather limited. Consequently, our study aims to evaluate its various effects, such as the diaphragmatic and pulmonary functions, as well as the analgesia for humeral fracture surgeries.
Patients and Methods: We enrolled 30 patients who were slated to undergo surgery for humeral fractures under the combined use of nerve block and general anesthesia. All the patients underwent CCB-CPBs under the guidance of an ultrasound and a nerve simulator. The anesthetic dosage consisted of 20 ml and 10 ml of 0.5% ropivacaine respectively. Following the operation, all the patients were transferred to the Post-Anesthesia Care Unit (PACU). The diaphragmatic excursion, spirometry outcomes, pain score, along with the sensory and motor block, were evaluated.
Results: The diaphragmatic excursion was significantly reduced during the post-block period in contrast to the pre-block period. The mean change in diaphragmatic excursion (with the mean value [SD]) was − 25.3 [48.6] %, accompanied by a P-value of 0.001. The forced vital capacity (FVC) during the post-block period was approximately 7% lower compared to that during the pre-block period, with a P-value of 0.032. The numerical rating scale (NRS) scores of the patients in the PACU were 0 (0– 0).
Conclusion: CCB-CPBs can result in a reduction in hemidiaphragm excursion and may slightly affect lung function to some extent. Nevertheless, they can provide a favorable analgesic effect for humeral fracture surgery. Therefore, patients with poor respiratory reserve should exercise caution when using it.

Keywords: ropivacaine, costoclavicular, humeral fracture, nerve block, hemidiaphragmatic paralysis