已发表论文

糖尿病肾病进展和针刺干预机制的研究进展

 

Authors Shan J, Cao Z, Yu S 

Received 4 August 2024

Accepted for publication 3 November 2024

Published 27 November 2024 Volume 2024:17 Pages 5593—5609

DOI https://doi.org/10.2147/IJGM.S490049

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor David E. Stec

Jinyi Shan,1 Ziyi Cao,2 Siming Yu3 

1School of Graduate Studies, Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China; 2The First Clinical Medical College of Shaanxi, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi Province, People’s Republic of China; 3Nephropathy Department, The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, People’s Republic of China

Correspondence: Siming Yu, Email yusiming010203@126.com

Abstract: Diabetic kidney disease (DKD) is a form of kidney damage resulting from diabetes and represents a common, severe complication of the disease. Globally, DKD is a leading cause of chronic kidney disease (CKD). DKD occurs in both type 1 and type 2 diabetes patients, with early clinical manifestations including microalbuminuria and hypertension. As the condition progresses, symptoms such as massive proteinuria, hypoalbuminemia, and severe edema may appear. The key to treating DKD lies in controlling blood glucose and blood pressure, reducing proteinuria, and slowing the deterioration of kidney function. Acupuncture, a traditional Chinese medicine treatment, has shown some therapeutic effects on DKD through mechanisms such as regulating blood glucose, improving renal blood flow and microcirculation, antioxidation and anti-inflammation, and modulating gut microbiota.

Keywords: diabetic kidney disease, acupuncture, mechanism, progress