已发表论文

双侧动眼神经麻痹:急性基底动脉闭塞桥接溶栓治疗的罕见并发症

 

Authors Lv S, Liu R, Sun J, Liu H, Guo X, Ding C

Received 7 April 2025

Accepted for publication 27 August 2025

Published 4 September 2025 Volume 2025:18 Pages 1141—1146

DOI https://doi.org/10.2147/IMCRJ.S532206

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Thomas E Hutson

Shuangyun Lv,1 Ronghui Liu,1 Jiapeng Sun,1 Hongmei Liu,1 Xin Guo,2– 4 Changxia Ding1 

1Department of Neurology, Huanghua Municipal People’s Hospital, Huanghua, Hebei, 061100, People’s Republic of China; 2Department of Neurology, the First Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China; 3Department of Neurology, Hebei Hospital, Xuanwu Hospital, Capital Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China; 4Neuromedical Technology Innovation Center of Hebei Province, Shijiazhuang, Hebei, 050000, People’s Republic of China

Correspondence: Changxia Ding, Department of Neurology, Huanghua Municipal People’s Hospital, Huanghua, Hebei, 061100, People’s Republic of China, Email DCX135827@163.com Xin Guo, Department of Neurology, the First Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China, Email Drguoxin@126.com

Abstract: Acute vertebrobasilar artery occlusion (AVBAO) accounts for only 1– 2% of ischemic stroke, but it has high disability and mortality rates. Mechanical thrombectomy (MT) combined with intravenous thrombolysis can quickly achieve vascular recanalization and significantly improve patient prognosis. This report describes a 73-year-old male who was admitted to the hospital in a coma due to AVBAO. After MT, successful recanalization of the basilar artery was achieved; however, the patient subsequently developed the rare but serious complication of bilateral oculomotor nerve palsy. The report emphasizes the need for careful preoperative planning, including detailed assessment of vascular anatomy and thrombus characteristics, and the importance of operator expertise. Improved intraoperative technique and close postoperative monitoring may help prevent complications such as vessel injury or embolic recurrence. Additionally, clinicians should be aware of the limitations of early DWI (Diffusion-weighted imaging) in detecting brainstem infarcts and of the need for clinical vigilance in the postoperative period.

Keywords: acute ischemic stroke, acute vertebrobasilar artery occlusion, mechanical thrombectomy, bilateral oculomotor nerve palsy