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已发表论文
中国罕见的角膜真菌病致病菌：黄色曲霉菌和长喙壳菌：病例报告
Authors Jiang LH, Sheng L, Luo J, Rong JC
Received 9 July 2025
Accepted for publication 12 September 2025
Published 18 September 2025 Volume 2025:18 Pages 4965—4970
DOI https://doi.org/10.2147/IDR.S550103
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Prof. Dr. Héctor M. Mora-Montes
Li-Hua Jiang,* Li Sheng,* Jie Luo, Jin-Cheng Rong
Yantai Yuhuangding Hospital, Qingdao University, Yantai, 264000, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Jin-Cheng Rong, Yantai Yuhuangding Hospital of Qingdao University, Yudong Road 20, Zhifu District, Yantai, Shandong, 264000, People’s Republic of China, Email jch100.cool@163.com
Abstract: Keratomycosis is a severe sight-threatening infection of the human cornea, accounting for around 50% of infectious keratitis cases both in China and globally. Its dominant fungal pathogens vary according to region and climate. It is caused by various pathogenic species with divergent clinical manifestations. Our knowledge on the phylogenetic data of fungal species for keratomycosis is still limited. Here, we describe two clinical cases of immunocompetent patients involving two rare fungal pathogens that cause fungal keratitis. Of these two pathogens, Achaetomium luteum is a novel pathogen for corneal infections, and another species, Exserohilum rostratum, is a rare cause of fungal keratitis. These two cases may provide more insights into the diagnosis, etiology, and treatment of keratomycosis.
Keywords: keratomycosis, etiology, dematiaceous fungi, Achaetomium luteum, Exserohilum rostratum
Yantai Yuhuangding Hospital, Qingdao University, Yantai, 264000, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Jin-Cheng Rong, Yantai Yuhuangding Hospital of Qingdao University, Yudong Road 20, Zhifu District, Yantai, Shandong, 264000, People’s Republic of China, Email jch100.cool@163.com
Abstract: Keratomycosis is a severe sight-threatening infection of the human cornea, accounting for around 50% of infectious keratitis cases both in China and globally. Its dominant fungal pathogens vary according to region and climate. It is caused by various pathogenic species with divergent clinical manifestations. Our knowledge on the phylogenetic data of fungal species for keratomycosis is still limited. Here, we describe two clinical cases of immunocompetent patients involving two rare fungal pathogens that cause fungal keratitis. Of these two pathogens, Achaetomium luteum is a novel pathogen for corneal infections, and another species, Exserohilum rostratum, is a rare cause of fungal keratitis. These two cases may provide more insights into the diagnosis, etiology, and treatment of keratomycosis.
Keywords: keratomycosis, etiology, dematiaceous fungi, Achaetomium luteum, Exserohilum rostratum