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已发表论文
针刺疗法及针刺联合疗法治疗腰椎间盘突出症所致坐骨神经痛的疗效和安全性：一项网络荟萃分析
Authors Ni D , Tong H, Wei S, Zheng Y, Wu W, Li M, Dong Y
Received 27 May 2025
Accepted for publication 3 September 2025
Published 16 September 2025 Volume 2025:18 Pages 4809—4832
DOI https://doi.org/10.2147/JPR.S542831
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Houman Danesh
Dongyi Ni,1 Haiyang Tong,1 Shen Wei,1 Yitong Zheng,2 Wenyan Wu,3 Min Li,1 Yunpeng Dong3,4
1Medical College of Acupuncture Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510000, People’s Republic of China; 2The Affiliated TCM Hospital of Guangzhou Medical University, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510000, People’s Republic of China; 3The Fifth Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510000, People’s Republic of China; 4Department of Orthopedics, Guangdong Provincial Second Hospital of Traditional Chinese Medicine, Guangdong Provincial Engineering Technology Research Institute of Traditional Chinese Medicine, Guangzhou, Guangdong, 510000, People’s Republic of China
Correspondence: Yunpeng Dong, Department of Orthopedics, Guangdong Provincial Second Hospital of Traditional Chinese Medicine, Guangdong Provincial Engineering Technology Research Institute of Traditional Chinese Medicine, No. 60 Hengfu Road, Yuexiu District, Guangzhou, People’s Republic of China, Tel +86 13570968068, Email dyptcm@163.com
Purpose: Sciatica is a common complication of lumbar disc herniation (LDH). This network meta-analysis compared the efficacy of acupuncture monotherapies, acupuncture versus conventional rehabilitation, and acupuncture monotherapy versus combination therapies for LDH-related sciatica.
Patients and Methods: We systematically searched PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, CQVIP, and CBM. Bayesian network meta-analysis was performed using RStudio and GEMTC. STATA generated network and funnel plots. Treatment rankings were assessed using the Surface Under the Cumulative Ranking curve (SUCRA). Bias risk was evaluated with the Cochrane Risk of Bias tool 2.0.
Results: According to SUCRA, in terms of total effective rate, the more effective intervention was electroacupuncture combined with cupping therapy (EA+Cupping, 92.93%); in terms of VAS, the better intervention was needle knife combined with rehabilitation therapy (NK+RT, 95.96%); in terms of ODI, the more effective intervention was electroacupuncture combined with cupping therapy (EA+Cupping, 98.03%); in terms of JOA, the best intervention was electrostimulation combined with rehabilitation therapy (ES+RT, 88.27%); in terms of IL-6 and TNF-α, the better intervention was electroacupuncture combined with electrostimulation (EA+ES, 99.99%).
Conclusion: Acupuncture combined with other therapies demonstrates superior efficacy compared to rehabilitation treatment. Specifically, NK+RT is possibly a more effective intervention for pain relief; EA+Cupping shows a better benefit in improving disability and quality of life; ES+RT is likely a more effective strategy for promoting neurological recovery; and EA+ES is possibly better in reducing inflammatory responses.
Keywords: acupuncture, related therapies, sciatica, lumbar disc herniation, network meta-analysis
1Medical College of Acupuncture Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510000, People’s Republic of China; 2The Affiliated TCM Hospital of Guangzhou Medical University, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510000, People’s Republic of China; 3The Fifth Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510000, People’s Republic of China; 4Department of Orthopedics, Guangdong Provincial Second Hospital of Traditional Chinese Medicine, Guangdong Provincial Engineering Technology Research Institute of Traditional Chinese Medicine, Guangzhou, Guangdong, 510000, People’s Republic of China
Correspondence: Yunpeng Dong, Department of Orthopedics, Guangdong Provincial Second Hospital of Traditional Chinese Medicine, Guangdong Provincial Engineering Technology Research Institute of Traditional Chinese Medicine, No. 60 Hengfu Road, Yuexiu District, Guangzhou, People’s Republic of China, Tel +86 13570968068, Email dyptcm@163.com
Purpose: Sciatica is a common complication of lumbar disc herniation (LDH). This network meta-analysis compared the efficacy of acupuncture monotherapies, acupuncture versus conventional rehabilitation, and acupuncture monotherapy versus combination therapies for LDH-related sciatica.
Patients and Methods: We systematically searched PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, CQVIP, and CBM. Bayesian network meta-analysis was performed using RStudio and GEMTC. STATA generated network and funnel plots. Treatment rankings were assessed using the Surface Under the Cumulative Ranking curve (SUCRA). Bias risk was evaluated with the Cochrane Risk of Bias tool 2.0.
Results: According to SUCRA, in terms of total effective rate, the more effective intervention was electroacupuncture combined with cupping therapy (EA+Cupping, 92.93%); in terms of VAS, the better intervention was needle knife combined with rehabilitation therapy (NK+RT, 95.96%); in terms of ODI, the more effective intervention was electroacupuncture combined with cupping therapy (EA+Cupping, 98.03%); in terms of JOA, the best intervention was electrostimulation combined with rehabilitation therapy (ES+RT, 88.27%); in terms of IL-6 and TNF-α, the better intervention was electroacupuncture combined with electrostimulation (EA+ES, 99.99%).
Conclusion: Acupuncture combined with other therapies demonstrates superior efficacy compared to rehabilitation treatment. Specifically, NK+RT is possibly a more effective intervention for pain relief; EA+Cupping shows a better benefit in improving disability and quality of life; ES+RT is likely a more effective strategy for promoting neurological recovery; and EA+ES is possibly better in reducing inflammatory responses.
Keywords: acupuncture, related therapies, sciatica, lumbar disc herniation, network meta-analysis