已发表论文

术中清醒麻醉及三维重建技术在三叉神经痛经皮微球囊压迫术中的应用

 

Authors Li X , Fan Y , Chen Z , Hui OY, Guo M , Feng G, Zhou J, Ling Y , Lin D 

Received 24 April 2025

Accepted for publication 8 September 2025

Published 16 September 2025 Volume 2025:18 Pages 4833—4843

DOI https://doi.org/10.2147/JPR.S534449

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 4

Editor who approved publication: Dr Jinlei Li

Xingke Li,1,2 Yanfeng Fan,1– 3 Ziyang Chen,1– 3 Ou-Yang Hui,1– 3 Min Guo,1– 3 Guili Feng,1– 3 Jianzhi Zhou,1– 3 Yuhui Ling,1– 3 Deliu Lin1– 3 

1Department of Neurosurgery, Guangdong Sanjiu Brain Hospital, Guangzhou, People’s Republic of China; 2Institute of Clinical Teaching Center, Jinan University, Guangzhou, People’s Republic of China; 3Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, People’s Republic of China

Correspondence: Deliu Lin, Email 370663906@qq.com

Objective: To examine the role of intraoperative awake anesthesia and the three-dimensional reconstruction technique in percutaneous microballoon compression (PBC) for the treatment of trigeminal neuralgia.
Methods: Seventy patients diagnosed with trigeminal neuralgia and admitted to Guangdong Sanjiu Brain Hospital from 2019 to 2022 were selected for the study.All patients were treated with PBC by three-dimensional (3D) reconstruction of preoperative and intraoperative images and intraoperative awake anesthesia. The duration of balloon compression during surgery was three minutes.After balloon compression during the procedure, the patient is awakened for effect assessment, allowing for real-time adjustments of the surgical strategy based on the evaluation.Postoperative pain relief was evaluated using the Brisman criteria.
Results: Pain completely disappeared immediately post-operation in 68 patients, and was significantly alleviated in two patients, with an efficacy rate of 100% and a cure rate of 97.1%. 60 patients experienced facial numbness on the affected side postoperatively, which showed different degrees of remission or disappearance within 6– 12 months after surgery. Eleven cases of herpes labialis (15.7%), one case of facial hematoma (1.4%), and three cases of postoperative psychiatric symptoms (4.3%) occurred, all of which recovered within 1– 2 weeks after surgery. Weakness in the masticatory muscles on the affected side was observed in four patients (5.7%), and all cases returned to normal within six months post-surgery.During follow-up 36– 60 months, there were five cases (7.1%) of pain recurrence on the affected side.
Conclusion: Awake anesthesia combined with 3D reconstruction technology for PBC surgery may provide a safer and more effective alternative for the treatment of trigeminal neuralgia.

Keywords: trigeminal neuralgia, awake anesthesia, three-dimensional reconstruction, microballoon compression