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已发表论文
傅氏皮内针治疗颈椎病的疗效和安全性：基于随机对照试验的系统评价和荟萃分析
Authors Shen Y , Chen J , Tang S, Xiao B
Received 30 April 2025
Accepted for publication 29 August 2025
Published 12 September 2025 Volume 2025:18 Pages 4759—4774
DOI https://doi.org/10.2147/JPR.S530364
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Krishnan Chakravarthy
Yating Shen,1,* Jing Chen,2,3,* Sen Tang,1 Binbin Xiao1
1The First Affiliated Hospital of Hunan Traditional Chinese Medical College (Hunan Province Directly Affliated TCM Hospital), Zhuzhou, Hunan, People’s Republic of China; 2College of Medical Imaging Laboratory and Rehabilitation, Xiangnan University, Chenzhou, Hunan, People’s Republic of China; 3Affiliated Hospital (Clinical College) of Xiangnan University, Xiangnan University, Chenzhou, Hunan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Binbin Xiao, The First Affiliated Hospital of Hunan Traditional Chinese Medical College (Hunan Province Directly Affiliated TCM Hospital), No. 571 Renmin Middle Road, Lusong District, Zhuzhou, Hunan, 412000, People’s Republic of China, Tel +86 15273300135, Email finseot@163.com
Background: Spondylosis (CS) is a prevalent condition that significantly impacts quality of life and overall health. Fu’s subcutaneous needling, a novel acupuncture technique, has been widely used to treat CS. This study employs a meta-analysis to comprehensively evaluate the efficacy of Fu’s subcutaneous needling in treating CS.
Methods: We searched PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), China Science Periodical Database (CSPD), Chinese Citation Database (CCD), and Chinese biomedical literature service system (CBM) databases for clinical trials on Fu’s subcutaneous needling for CS, from inception to March 1, 2025. The quality of the included studies was assessed using the Cochrane Handbook for Systematic Reviews, and meta-analysis was performed using Stata 16.0.
Results: A total of 46 studies involving 3767 cases were included. The results showed that the Fu’s subcutaneous needling group had a higher effective rate than the control group (RR: 1.17, 95% CI: 1.14– 1.20, p < 0.05). The Fu’s subcutaneous needling group also had lower Visual Analog Scale (VAS) scores (WMD: − 1.55, 95% CI: − 1.98 to − 1.12, p < 0.05), lower Northwick Park Neck Pain Questionnaire (NPQ) scores (WMD: − 2.65, 95% CI: − 5.27 to − 0.03, p < 0.05), and lower Neck Disability Index (NDI) scores (WMD: − 3.40, 95% CI: − 6.59 to − 0.21, p < 0.05) compared to the control group. The Fu’s subcutaneous needling group also demonstrated higher safety (RR: 0.32, 95% CI: 0.13– 0.75, p < 0.05). Subgroup analysis indicated that Fu’s subcutaneous needling was effective across various subtypes of CS and showed significant advantages over other treatment modalities. The Efficacy of Fu’s subcutaneous needling improved with longer treatment durations.
Conclusion: Fu’s subcutaneous needling is effective and safe for treating CS. Due to the limited number of included studies, further research is needed to confirm these findings.
Keywords: Fu’s subcutaneous needling, spondylosis, efficacy, safety, systematic review, meta-analysis
1The First Affiliated Hospital of Hunan Traditional Chinese Medical College (Hunan Province Directly Affliated TCM Hospital), Zhuzhou, Hunan, People’s Republic of China; 2College of Medical Imaging Laboratory and Rehabilitation, Xiangnan University, Chenzhou, Hunan, People’s Republic of China; 3Affiliated Hospital (Clinical College) of Xiangnan University, Xiangnan University, Chenzhou, Hunan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Binbin Xiao, The First Affiliated Hospital of Hunan Traditional Chinese Medical College (Hunan Province Directly Affiliated TCM Hospital), No. 571 Renmin Middle Road, Lusong District, Zhuzhou, Hunan, 412000, People’s Republic of China, Tel +86 15273300135, Email finseot@163.com
Background: Spondylosis (CS) is a prevalent condition that significantly impacts quality of life and overall health. Fu’s subcutaneous needling, a novel acupuncture technique, has been widely used to treat CS. This study employs a meta-analysis to comprehensively evaluate the efficacy of Fu’s subcutaneous needling in treating CS.
Methods: We searched PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), China Science Periodical Database (CSPD), Chinese Citation Database (CCD), and Chinese biomedical literature service system (CBM) databases for clinical trials on Fu’s subcutaneous needling for CS, from inception to March 1, 2025. The quality of the included studies was assessed using the Cochrane Handbook for Systematic Reviews, and meta-analysis was performed using Stata 16.0.
Results: A total of 46 studies involving 3767 cases were included. The results showed that the Fu’s subcutaneous needling group had a higher effective rate than the control group (RR: 1.17, 95% CI: 1.14– 1.20, p < 0.05). The Fu’s subcutaneous needling group also had lower Visual Analog Scale (VAS) scores (WMD: − 1.55, 95% CI: − 1.98 to − 1.12, p < 0.05), lower Northwick Park Neck Pain Questionnaire (NPQ) scores (WMD: − 2.65, 95% CI: − 5.27 to − 0.03, p < 0.05), and lower Neck Disability Index (NDI) scores (WMD: − 3.40, 95% CI: − 6.59 to − 0.21, p < 0.05) compared to the control group. The Fu’s subcutaneous needling group also demonstrated higher safety (RR: 0.32, 95% CI: 0.13– 0.75, p < 0.05). Subgroup analysis indicated that Fu’s subcutaneous needling was effective across various subtypes of CS and showed significant advantages over other treatment modalities. The Efficacy of Fu’s subcutaneous needling improved with longer treatment durations.
Conclusion: Fu’s subcutaneous needling is effective and safe for treating CS. Due to the limited number of included studies, further research is needed to confirm these findings.
Keywords: Fu’s subcutaneous needling, spondylosis, efficacy, safety, systematic review, meta-analysis